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Metabolic stress modulates Alzheimer's ?-secretase gene transcription via SIRT1-PPAR?-PGC-1 in neurons.
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Metabolic stress modulates Alzheimer's ?-secretase gene transcription via SIRT1-PPAR?-PGC-1 in neurons.
Metabolic stress modulates Alzheimer's ?-secretase gene transcription via SIRT1-PPAR?-PGC-1 in neurons. Cell Metab. 2013 May 07; 17(5):685-94.
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PubMed
subject areas
Acetylation
Alzheimer Disease
Amyloid Precursor Protein Secretases
Animals
Aspartic Acid Endopeptidases
Down-Regulation
Mice
Mice, Inbred C57BL
Neurons
Nitric Oxide Synthase Type III
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
PPAR gamma
Promoter Regions, Genetic
Rats
Sirtuin 1
Stress, Physiological
Transcription Factors
Transcription, Genetic
Up-Regulation
authors with profiles
Narayan R. Bhat