"Coagulase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.
| Descriptor ID |
D003030
|
| MeSH Number(s) |
D08.811.277.656.300.174 D12.776.097.181
|
| Concept/Terms |
Staphylococcal Clumping Factor- Staphylococcal Clumping Factor
- Clumping Factor, Staphylococcal
- Factor, Staphylococcal Clumping
- Clumping Factor (Staphylococcal)
|
Below are MeSH descriptors whose meaning is more general than "Coagulase".
Below are MeSH descriptors whose meaning is more specific than "Coagulase".
This graph shows the total number of publications written about "Coagulase" by people in this website by year, and whether "Coagulase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Coagulase" by people in Profiles.
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Time to positivity of blood cultures in neonatal late-onset bacteraemia. Arch Dis Child Fetal Neonatal Ed. 2022 Nov; 107(6):583-588.
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Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial. JAMA. 2018 09 25; 320(12):1249-1258.
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The SaeRS Two-Component System Controls Survival of Staphylococcus aureus in Human Blood through Regulation of Coagulase. Front Cell Infect Microbiol. 2017; 7:204.
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Drug evaluation: tefibazumab--a monoclonal antibody against staphylococcal infection. Curr Opin Mol Ther. 2006 Oct; 8(5):455-60.
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Sequence analysis of dru regions from methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococcal isolates. Microb Drug Resist. 2001; 7(1):1-12.
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Topoisomerase sequences of coagulase-negative staphylococcal isolates resistant to ciprofloxacin or trovafloxacin. Antimicrob Agents Chemother. 1999 Jul; 43(7):1631-7.
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Widespread colonization of personnel at a Veterans Affairs medical center by methicillin-resistant, coagulase-negative Staphylococcus. Clin Infect Dis. 1993 Sep; 17(3):380-8.
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Colonization of the female genital tract with Staphylococcus saprophyticus. J Clin Microbiol. 1992 Nov; 30(11):2975-9.
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Relatedness of strains of methicillin-resistant coagulase-negative Staphylococcus colonizing hospital personnel and producing bacteremias in a neonatal intensive care unit. Pediatr Infect Dis J. 1992 Nov; 11(11):935-40.
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Reliability of latex agglutination tests for identification of Staphylococcus aureus resistant to oxacillin. J Clin Microbiol. 1986 Dec; 24(6):1104-6.