"Lac Repressors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bacterial repressor proteins that bind to the LAC OPERON and thereby prevent the synthesis of proteins involved in catabolism of LACTOSE. When lactose levels are high lac repressors undergo an allosteric change that causes their release from the DNA and the resumption of lac operon transcription.
| Descriptor ID |
D056968
|
| MeSH Number(s) |
D12.776.097.521 D12.776.260.703.600 D12.776.930.780.781
|
| Concept/Terms |
Lac Repressors- Lac Repressors
- Repressors, Lac
- LacI Proteins
- Proteins, LacI
- Lac Repressor
- Repressor, Lac
|
Below are MeSH descriptors whose meaning is more general than "Lac Repressors".
Below are MeSH descriptors whose meaning is more specific than "Lac Repressors".
This graph shows the total number of publications written about "Lac Repressors" by people in this website by year, and whether "Lac Repressors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lac Repressors" by people in Profiles.
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Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells. Proc Natl Acad Sci U S A. 2014 Oct 21; 111(42):E4449-57.
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Quantitation of the DNA tethering effect in long-range DNA looping in vivo and in vitro using the Lac and ? repressors. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):349-54.
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Doc-mediated cell killing in Shigella flexneri using a C1/LacI controlled expression system. FEMS Microbiol Lett. 2002 Oct 08; 215(2):237-42.
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Inducible retroviral vectors regulated by lac repressor in mammalian cells. Gene. 1996 Dec 12; 183(1-2):137-42.