"Phorbol Esters" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tumor-promoting compounds obtained from CROTON OIL (Croton tiglium). Some of these are used in cell biological experiments as activators of protein kinase C.
| Descriptor ID |
D010703
|
| MeSH Number(s) |
D02.455.849.291.500.510
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phorbol Esters".
Below are MeSH descriptors whose meaning is more specific than "Phorbol Esters".
This graph shows the total number of publications written about "Phorbol Esters" by people in this website by year, and whether "Phorbol Esters" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 2 | 2 | 4 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phorbol Esters" by people in Profiles.
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miR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53. Blood. 2009 Sep 03; 114(10):2181-92.
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Involvement of protein kinase C in melatonin's oncostatic effect in C6 glioma cells. J Pineal Res. 2007 Oct; 43(3):239-44.
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Phorbol ester treatment of K562 cells regulates the transcriptional activity of AML1c through phosphorylation. J Biol Chem. 2004 Dec 17; 279(51):53116-25.
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Isoenzyme-specific translocation of protein kinase C (PKC)betaII and not PKCbetaI to a juxtanuclear subset of recycling endosomes: involvement of phospholipase D. J Biol Chem. 2004 Jul 02; 279(27):28251-6.
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Regulated internalization and phosphorylation of the native norepinephrine transporter in response to phorbol esters. Evidence for localization in lipid rafts and lipid raft-mediated internalization. J Biol Chem. 2004 Apr 30; 279(18):19315-26.
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Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization. J Mol Neurosci. 2004; 24(1):137-43.
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The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes. J Biol Chem. 2004 Mar 26; 279(13):12009-19.
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Integrin shedding as a mechanism of cellular adaptation during cardiac growth. Am J Physiol Heart Circ Physiol. 2003 Jun; 284(6):H2227-34.
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Modulation of human glutamate transporter activity by phorbol ester. J Neurochem. 1998 Mar; 70(3):993-1000.
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Mechanisms of ceramide-mediated apoptosis. Adv Exp Med Biol. 1997; 407:145-9.