Tetradecanoylphorbol Acetate
"Tetradecanoylphorbol Acetate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.
| Descriptor ID |
D013755
|
| MeSH Number(s) |
D02.455.849.291.500.510.850
|
| Concept/Terms |
Tetradecanoylphorbol Acetate- Tetradecanoylphorbol Acetate
- Acetate, Tetradecanoylphorbol
- 12-O-Tetradecanoyl Phorbol 13-Acetate
- 12 O Tetradecanoyl Phorbol 13 Acetate
- 13-Acetate, 12-O-Tetradecanoyl Phorbol
- Phorbol 13-Acetate, 12-O-Tetradecanoyl
- Phorbol Myristate Acetate
- Acetate, Phorbol Myristate
- Myristate Acetate, Phorbol
- 12-Myristoyl-13-acetylphorbol
- 12 Myristoyl 13 acetylphorbol
|
Below are MeSH descriptors whose meaning is more general than "Tetradecanoylphorbol Acetate".
Below are MeSH descriptors whose meaning is more specific than "Tetradecanoylphorbol Acetate".
This graph shows the total number of publications written about "Tetradecanoylphorbol Acetate" by people in this website by year, and whether "Tetradecanoylphorbol Acetate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 2 | 3 |
| 1995 | 0 | 7 | 7 |
| 1996 | 0 | 5 | 5 |
| 1997 | 4 | 2 | 6 |
| 1998 | 3 | 2 | 5 |
| 1999 | 1 | 4 | 5 |
| 2000 | 1 | 5 | 6 |
| 2001 | 0 | 4 | 4 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 5 | 5 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 4 | 4 |
| 2007 | 0 | 4 | 4 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2014 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tetradecanoylphorbol Acetate" by people in Profiles.
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Co-ordinated activation of classical and novel PKC isoforms is required for PMA-induced mTORC1 activation. PLoS One. 2017; 12(9):e0184818.
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In vitro evaluation of the effects of perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) on IL-2 production in human T-cells. J Appl Toxicol. 2015 May; 35(5):459-65.
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Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway. J Biol Chem. 2014 Aug 08; 289(32):22401-12.
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Phospholipase C and protein kinase C-? 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation. Mol Endocrinol. 2011 Dec; 25(12):2144-56.
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Delayed phosphorylation of classical protein kinase C (PKC) substrates requires PKC internalization and formation of the pericentrion in a phospholipase D (PLD)-dependent manner. J Biol Chem. 2011 Jun 03; 286(22):19340-53.
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Cellular phenotype transformation occurs during thoracic aortic aneurysm development. J Thorac Cardiovasc Surg. 2010 Sep; 140(3):653-9.
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Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity. Biochem J. 2009 May 01; 419(3):669-79.
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Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid. J Biol Chem. 2009 May 08; 284(19):12979-88.
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Involvement of acid beta-glucosidase 1 in the salvage pathway of ceramide formation. J Biol Chem. 2009 May 08; 284(19):12972-8.
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Neonatal rat cardiac fibroblasts express three types of voltage-gated K+ channels: regulation of a transient outward current by protein kinase C. Am J Physiol Heart Circ Physiol. 2008 Feb; 294(2):H1010-7.