GTP-Binding Proteins

"GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Regulatory proteins that act as molecular switches. They control a wide range of biological processes including: receptor signaling, intracellular signal transduction pathways, and protein synthesis. Their activity is regulated by factors that control their ability to bind to and hydrolyze GTP to GDP. EC 3.6.1.-.

Descriptor ID	D019204
MeSH Number(s)	D08.811.277.040.330.300 D12.776.157.325
Concept/Terms	GTP-Binding Proteins GTP-Binding Proteins GTP Binding Proteins Proteins, GTP-Binding G-Proteins G Proteins GTP-Binding Protein GTP Binding Protein Protein, GTP-Binding Guanine Nucleotide Regulatory Proteins GTP-Regulatory Protein GTP Regulatory Protein Protein, GTP-Regulatory GTP-Regulatory Proteins GTP Regulatory Proteins Proteins, GTP-Regulatory Guanine Nucleotide Coupling Protein G-Protein G Protein

Below are MeSH descriptors whose meaning is more general than "GTP-Binding Proteins".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
GTP Phosphohydrolases [D08.811.277.040.330]
GTP-Binding Proteins [D08.811.277.040.330.300]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
GTP-Binding Proteins [D12.776.157.325]

Below are MeSH descriptors whose meaning is related to "GTP-Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "GTP-Binding Proteins" by people in this website by year, and whether "GTP-Binding Proteins" was a major or minor topic of these publications.

Bar chart showing 145 publications over 27 distinct years, with a maximum of 16 publications in 1998

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	6	0	6
1994	6	4	10
1995	10	5	15
1996	9	2	11
1997	10	0	10
1998	12	4	16
1999	8	2	10
2000	3	2	5
2001	4	0	4
2002	9	5	14
2003	4	1	5
2004	1	3	4
2005	1	2	3
2006	6	1	7
2007	1	2	3
2008	0	1	1
2009	1	0	1
2010	2	2	4
2011	2	0	2
2012	0	1	1
2013	2	2	4
2014	0	2	2
2015	1	0	1
2016	1	0	1
2017	2	0	2
2018	0	2	2
2020	1	0	1

Below are the most recent publications written about "GTP-Binding Proteins" by people in Profiles.

Malpe MS, McSwain LF, Kudyba K, Ng CL, Nicholson J, Brady M, Qian Y, Choksi V, Hudson AG, Parrott BB, Schulz C. G-protein signaling is required for increasing germline stem cell division frequency in response to mating in Drosophila males. Sci Rep. 2020 03 03; 10(1):3888.

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Mahler SV, Brodnik ZD, Cox BM, Buchta WC, Bentzley BS, Quintanilla J, Cope ZA, Lin EC, Riedy MD, Scofield MD, Messinger J, Ruiz CM, Riegel AC, España RA, Aston-Jones G. Chemogenetic Manipulations of Ventral Tegmental Area Dopamine Neurons Reveal Multifaceted Roles in Cocaine Abuse. J Neurosci. 2019 01 16; 39(3):503-518.

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Andersen HK, Piroli GG, Walsh KB. A real time screening assay for cannabinoid CB1 receptor-mediated signaling. J Pharmacol Toxicol Methods. 2018 Nov - Dec; 94(Pt 1):44-49.

View in: PubMed
Lai TS, Lindberg RA, Zhou HL, Haroon ZA, Dewhirst MW, Hausladen A, Juang YL, Stamler JS, Greenberg CS. Endothelial cell-surface tissue transglutaminase inhibits neutrophil adhesion by binding and releasing nitric oxide. Sci Rep. 2017 11 23; 7(1):16163.

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Walsh KB, Gay EA, Blough BE, Geurkink DW. N-(2-methoxyphenyl) benzenesulfonamide, a novel regulator of neuronal G protein-gated inward rectifier K+ channels. Eur J Pharmacol. 2017 Nov 15; 815:233-240.

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Lai TS, Lin CJ, Greenberg CS. Role of tissue transglutaminase-2 (TG2)-mediated aminylation in biological processes. Amino Acids. 2017 03; 49(3):501-515.

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Robichaux WG, Oner SS, Lanier SM, Blumer JB. Direct Coupling of a Seven-Transmembrane-Span Receptor to a Gai G-Protein Regulatory Motif Complex. Mol Pharmacol. 2015 Aug; 88(2):231-7.

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Kumar A, Hu J, LaVoie HA, Walsh KB, DiPette DJ, Singh US. Conformational changes and translocation of tissue-transglutaminase to the plasma membranes: role in cancer cell migration. BMC Cancer. 2014 Apr 11; 14:256.

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Branham-O'Connor M, Robichaux WG, Zhang XK, Cho H, Kehrl JH, Lanier SM, Blumer JB. Defective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3). J Biol Chem. 2014 Apr 11; 289(15):10738-10747.

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Blumer JB, Lanier SM. Activators of G protein signaling exhibit broad functionality and define a distinct core signaling triad. Mol Pharmacol. 2014 Mar; 85(3):388-96.

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