"Somatomedins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They cause sulfate incorporation into collagen, RNA, and DNA synthesis, which are prerequisites to cell division and growth of the organism.
Descriptor ID |
D013002
|
MeSH Number(s) |
D12.644.276.937 D12.776.124.862 D12.776.467.937 D23.529.937
|
Concept/Terms |
Somatomedins- Somatomedins
- Sulfation Factor
- Factor, Sulfation
- Somatomedin
- Insulin Like Growth Factors
- Insulin-Like Growth Factors
- Factors, Insulin-Like Growth
- Growth Factors, Insulin-Like
|
Below are MeSH descriptors whose meaning is more general than "Somatomedins".
Below are MeSH descriptors whose meaning is more specific than "Somatomedins".
This graph shows the total number of publications written about "Somatomedins" by people in this website by year, and whether "Somatomedins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 2 | 2 |
2006 | 2 | 0 | 2 |
2010 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Somatomedins" by people in Profiles.
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Henning AN, Haag JD, Smits BM, Gould MN. The Non-coding Mammary Carcinoma Susceptibility Locus, Mcs5c, Regulates Pappa Expression via Age-Specific Chromatin Folding and Allele-Dependent DNA Methylation. PLoS Genet. 2016 08; 12(8):e1006261.
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Su Y, Nishimoto T, Feghali-Bostwick C. IGFBP-5 Promotes Fibrosis Independently of Its Translocation to the Nucleus and Its Interaction with Nucleolin and IGF. PLoS One. 2015; 10(6):e0130546.
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Huang Y, Harrison MR, Osorio A, Kim J, Baugh A, Duan C, Sucov HM, Lien CL. Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration. PLoS One. 2013; 8(6):e67266.
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Kim TH, Chow YH, Gill SE, Schnapp LM. Effect of insulin-like growth factor blockade on hyperoxia-induced lung injury. Am J Respir Cell Mol Biol. 2012 Sep; 47(3):372-8.
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Rosenzweig SA, Atreya HS. Defining the pathway to insulin-like growth factor system targeting in cancer. Biochem Pharmacol. 2010 Oct 15; 80(8):1115-24.
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El-Shewy HM, Johnson KR, Lee MH, Jaffa AA, Obeid LM, Luttrell LM. Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors. J Biol Chem. 2006 Oct 20; 281(42):31399-407.
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Schnapp LM, Donohoe S, Chen J, Sunde DA, Kelly PM, Ruzinski J, Martin T, Goodlett DR. Mining the acute respiratory distress syndrome proteome: identification of the insulin-like growth factor (IGF)/IGF-binding protein-3 pathway in acute lung injury. Am J Pathol. 2006 Jul; 169(1):86-95.
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Harmon C, Willoughby DF, Floyd C. A lesson in early morning hyperglycemia. Nurse Pract. 2004 Nov; 29(11):58-63.
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Guttridge DC. Signaling pathways weigh in on decisions to make or break skeletal muscle. Curr Opin Clin Nutr Metab Care. 2004 Jul; 7(4):443-50.
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Zetterström C, Fang C, Benjamin A, Rosenzweig SA. Characterization of a novel receptor in toad retina with dual specificity for insulin and insulin-like growth factor I. J Neurochem. 1991 Oct; 57(4):1332-9.