"ELAV Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of RRM PROTEINS that are homologues of ELAV protein, Drosophila. They were initially identified in humans as the targets of autoantibodies in patients with PARANEOPLASTIC ENCEPHALOMYELITIS. They regulate GENE EXPRESSION at the post-transcriptional level.
| Descriptor ID |
D051959
|
| MeSH Number(s) |
D12.776.157.725.813.500 D12.776.631.520 D12.776.664.962.813.500
|
| Concept/Terms |
ELAV Proteins- ELAV Proteins
- Proteins, ELAV
- ELAV Protein
- Protein, ELAV
- Hu Antigens
- Antigens, Hu
- Embryonic Lethal, Abnormal Vision-Like Proteins
- Embryonic Lethal, Abnormal Vision Like Proteins
- Hu Paraneoplastic Encephalomyelitis Antigens
|
Below are MeSH descriptors whose meaning is more general than "ELAV Proteins".
Below are MeSH descriptors whose meaning is more specific than "ELAV Proteins".
This graph shows the total number of publications written about "ELAV Proteins" by people in this website by year, and whether "ELAV Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 3 | 1 | 4 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "ELAV Proteins" by people in Profiles.
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Ribonucleoprotein therapy in Alzheimer's disease? Aging (Albany NY). 2014 Jun; 6(6):428-9.
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Inhibition of caspases protects mice from radiation-induced oral mucositis and abolishes the cleavage of RNA-binding protein HuR. J Biol Chem. 2014 Feb 07; 289(6):3487-500.
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Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs. Nucleic Acids Res. 2014 Jan; 42(2):1196-208.
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miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR. Sci Signal. 2013 Jul 30; 6(286):ra63.
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Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination. Nat Commun. 2013; 4:2939.
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The role of acid sphingomyelinase and caspase 5 in hypoxia-induced HuR cleavage and subsequent apoptosis in hepatocytes. Biochim Biophys Acta. 2012 Dec; 1821(12):1453-61.
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LincRNA-p21 suppresses target mRNA translation. Mol Cell. 2012 Aug 24; 47(4):648-55.
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Caspase-mediated cleavage of RNA-binding protein HuR regulates c-Myc protein expression after hypoxic stress. J Biol Chem. 2011 Sep 16; 286(37):32333-43.
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Novel mechanisms in the regulation of G protein-coupled receptor trafficking to the plasma membrane. J Biol Chem. 2010 Oct 29; 285(44):33816-25.
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Regulation of Bcl-2 expression by HuR in HL60 leukemia cells and A431 carcinoma cells. Mol Cancer Res. 2009 Aug; 7(8):1354-66.