"Guanidines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of iminourea derivatives. The parent compound has been isolated from mushrooms, corn germ, rice hulls, mussels, earthworms, and turnip juice. Derivatives may have antiviral and antifungal properties.
| Descriptor ID |
D006146
|
| MeSH Number(s) |
D02.078.370
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Guanidines".
Below are MeSH descriptors whose meaning is more specific than "Guanidines".
This graph shows the total number of publications written about "Guanidines" by people in this website by year, and whether "Guanidines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanidines" by people in Profiles.
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Neurovascular protection in voltage-gated proton channel Hv1 knock-out rats after ischemic stroke: interaction with Na+ /H+ exchanger-1 antagonism. Physiol Rep. 2019 08; 7(13):e14142.
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Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis. Prostaglandins Other Lipid Mediat. 2017 05; 130:47-56.
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Nonpeptide small molecule agonist and antagonist original leads for neuropeptide FF1 and FF2 receptors. J Med Chem. 2014 Nov 13; 57(21):8903-27.
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Regulation of nitric oxide production by d-opioid receptors during glaucomatous injury. PLoS One. 2014; 9(10):e110397.
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The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines. Amino Acids. 2014 Mar; 46(3):585-94.
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Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12; 52(21):6515-8.
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Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide. Amino Acids. 2007 Aug; 33(2):231-40.
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Novel alkylpolyaminoguanidines and alkylpolyaminobiguanides with potent antitrypanosomal activity. Bioorg Med Chem Lett. 2006 Jun 15; 16(12):3229-32.
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Direct inhibition of the sodium/hydrogen exchanger after prolonged regional ischemia improves contractility on reperfusion independent of myocardial viability. J Thorac Cardiovasc Surg. 2003 Nov; 126(5):1489-97.
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Safety and efficacy of nebulized zanamivir in hospitalized patients with serious influenza. Antivir Ther. 2003 Jun; 8(3):183-90.