Mitogen-Activated Protein Kinase 10
"Mitogen-Activated Protein Kinase 10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a role in stress-induced neuronal APOPTOSIS. Several isoforms of the protein with molecular sizes of 47 kDa and 52 kDa exist due to multiple ALTERNATIVE SPLICING.
| Descriptor ID |
D048057
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.374.800 D12.644.360.450.340.800 D12.776.476.450.340.800
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| Concept/Terms |
Mitogen-Activated Protein Kinase 10- Mitogen-Activated Protein Kinase 10
- Mitogen Activated Protein Kinase 10
- c-jun Kinase 3
- Kinase 3, c-jun
- c jun Kinase 3
- Mitogen Activated Protein Kinase p49(3F12)
- p49 3F12 Kinase
- 3F12 Kinase, p49
- p49(3F12) SAP Kinase
- MAPK10 Mitogen-Activated Protein Kinase
- MAPK10 Mitogen Activated Protein Kinase
- Stress-Activated Protein Kinase JNK3
- Stress Activated Protein Kinase JNK3
- c-jun N-Terminal Kinase 3
- c jun N Terminal Kinase 3
- JNK3 Mitogen Activated Protein Kinase
- MAP Kinase p49(3F12)
- p54-SAPK(beta)
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Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 10".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 10".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 10" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 10" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 10" by people in Profiles.
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JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction. J Biol Chem. 2007 Aug 31; 282(35):25940-9.
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Strategies for the design of potent and selective kinase inhibitors. Curr Pharm Des. 2005; 11(14):1845-63.
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Identification of a motif in the carboxyl terminus of beta -arrestin2 responsible for activation of JNK3. J Biol Chem. 2001 Jul 27; 276(30):27770-7.
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Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science. 2000 Nov 24; 290(5496):1574-7.
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ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice. Mol Cell Biol. 2000 Nov; 20(21):8026-34.
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Regulation of dual-specificity phosphatases M3/6 and hVH5 by phorbol esters. Analysis of a delta-like domain. J Biol Chem. 2000 Oct 13; 275(41):31755-62.