"Aurora Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of highly conserved serine-threonine kinases that are involved in the regulation of MITOSIS. They are involved in many aspects of cell division, including centrosome duplication, SPINDLE APPARATUS formation, chromosome alignment, attachment to the spindle, checkpoint activation, and CYTOKINESIS.
| Descriptor ID |
D064127
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.103 D12.776.167.049
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Aurora Kinases".
Below are MeSH descriptors whose meaning is more specific than "Aurora Kinases".
This graph shows the total number of publications written about "Aurora Kinases" by people in this website by year, and whether "Aurora Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Aurora Kinases" by people in Profiles.
-
Discovery of N-phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors. J Med Chem. 2010 Jun 10; 53(11):4367-78.
-
HEF1 is a crucial mediator of the proliferative effects of prostaglandin E(2) on colon cancer cells. Cancer Res. 2010 Jan 15; 70(2):824-31.
-
Cell cycle kinases as therapeutic targets for cancer. Nat Rev Drug Discov. 2009 Jul; 8(7):547-66.