"Caspase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
| Descriptor ID |
D053148
|
| MeSH Number(s) |
D08.811.277.656.262.500.126.350.300 D08.811.277.656.300.200.126.350.300 D12.644.360.075.405.350.300 D12.776.476.075.405.350.300
|
| Concept/Terms |
Procaspase-3- Procaspase-3
- Procaspase 3
- Pro-Caspase-3
- Pro Caspase 3
|
Below are MeSH descriptors whose meaning is more general than "Caspase 3".
Below are MeSH descriptors whose meaning is more specific than "Caspase 3".
This graph shows the total number of publications written about "Caspase 3" by people in this website by year, and whether "Caspase 3" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 4 | 4 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 8 | 8 |
| 2004 | 0 | 8 | 8 |
| 2005 | 0 | 8 | 8 |
| 2006 | 0 | 8 | 8 |
| 2007 | 0 | 9 | 9 |
| 2008 | 1 | 7 | 8 |
| 2009 | 2 | 9 | 11 |
| 2010 | 1 | 10 | 11 |
| 2011 | 1 | 8 | 9 |
| 2012 | 2 | 8 | 10 |
| 2013 | 2 | 5 | 7 |
| 2014 | 1 | 8 | 9 |
| 2015 | 0 | 4 | 4 |
| 2016 | 1 | 4 | 5 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 3 | 4 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Caspase 3" by people in Profiles.
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Manzamine-A Alters In Vitro Calvarial Osteoblast Function. Mar Drugs. 2022 Oct 19; 20(10).
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Small-molecule inhibitors of the PERK-mediated Unfolded Protein Response signaling pathway in targeted therapy for colorectal cancer. Pol Przegl Chir. 2022 Mar 15; 94(6):17-25.
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In?Vitro Effect of Dovitinib (TKI258), a Multi-Target Angiokinase Inhibitor on Aggressive Meningioma Cells. Cancer Invest. 2020 Jul; 38(6):349-355.
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Quercetin and Sodium Butyrate Synergistically Increase Apoptosis in Rat C6 and Human T98G Glioblastoma Cells Through Inhibition of Autophagy. Neurochem Res. 2019 Jul; 44(7):1715-1725.
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Endoplasmic reticulum stress, autophagic and apoptotic cell death, and immune activation by a natural triterpenoid in human prostate cancer cells. J Cell Biochem. 2019 04; 120(4):6264-6276.
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Relationship between blastocoel cell-free DNA and day-5 blastocyst morphology. J Assist Reprod Genet. 2018 Aug; 35(8):1497-1501.
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Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3. J Biol Chem. 2018 06 22; 293(25):9784-9800.
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Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status. J Med Chem. 2018 03 22; 61(6):2589-2603.
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Induction of apoptosis in human glioma cell lines of various grades through the ROS-mediated mitochondrial pathway and caspase activation by Rhaponticum carthamoides transformed root extract. Mol Cell Biochem. 2018 Aug; 445(1-2):89-97.
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Immune complexes containing malondialdehyde (MDA) LDL induce apoptosis in human macrophages. Clin Immunol. 2018 02; 187:1-9.