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Leone, Gustavo
One or more keywords matched the following items that are connected to Leone, Gustavo
Item TypeName
Concept Membrane Proteins
Concept LDL-Receptor Related Proteins
Concept DNA-Binding Proteins
Concept ras GTPase-Activating Proteins
Concept Muscle Proteins
Concept Proto-Oncogene Proteins c-rel
Concept Hedgehog Proteins
Concept HSP70 Heat-Shock Proteins
Concept Mitochondrial Proteins
Concept Helminth Proteins
Concept Carrier Proteins
Concept Proto-Oncogene Proteins c-bcl-2
Concept Chromosomal Proteins, Non-Histone
Concept Cell Cycle Proteins
Concept Nuclear Proteins
Concept Recombinant Proteins
Concept Fusion Proteins, bcr-abl
Concept Mutant Proteins
Concept S100 Proteins
Concept Proto-Oncogene Proteins c-mdm2
Concept Proto-Oncogene Proteins c-met
Concept Viral Proteins
Concept Repressor Proteins
Concept HSP90 Heat-Shock Proteins
Concept Cornified Envelope Proline-Rich Proteins
Concept Bone Morphogenetic Proteins
Concept Proto-Oncogene Proteins c-akt
Concept Proteins
Concept Microtubule-Associated Proteins
Concept Homeodomain Proteins
Concept Oncogene Proteins, Viral
Concept Proto-Oncogene Proteins c-sis
Concept Adaptor Proteins, Signal Transducing
Concept Proto-Oncogene Proteins c-myc
Concept Retinoblastoma Binding Proteins
Concept Proto-Oncogene Proteins c-raf
Concept ras Proteins
Concept Recombinant Fusion Proteins
Concept Inhibitor of Apoptosis Proteins
Concept Capsid Proteins
Concept Saccharomyces cerevisiae Proteins
Concept Proto-Oncogene Proteins c-jun
Concept Neoplasm Proteins
Concept Caenorhabditis elegans Proteins
Concept Proto-Oncogene Proteins p21(ras)
Concept Adenovirus E2 Proteins
Concept Arabidopsis Proteins
Concept Apoptosis Regulatory Proteins
Concept Proto-Oncogene Proteins
Concept Tumor Suppressor Proteins
Concept RNA-Binding Proteins
Academic Article Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis.
Academic Article Structural characterization of Rasgrf1 and a novel linked imprinted locus.
Academic Article Inactivation of E2F3 results in centrosome amplification.
Academic Article Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation.
Academic Article Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel-/- B cells.
Academic Article Bone morphogenetic protein 3B silencing in non-small-cell lung cancer.
Academic Article Aberrant regulation of survivin by the RB/E2F family of proteins.
Academic Article Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.
Academic Article Distinct capacities of individual E2Fs to induce cell cycle re-entry in postmitotic lens fiber cells of transgenic mice.
Academic Article E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7.
Academic Article Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations.
Academic Article Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions.
Academic Article Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis.
Academic Article CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells.
Academic Article Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development.
Academic Article E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
Academic Article Allele-specific tumor spectrum in pten knockin mice.
Academic Article Cell proliferation in the absence of E2F1-3.
Academic Article S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways.
Academic Article Evidence for a stepwise program of extrathymic T cell development within the human tonsil.
Academic Article Atypical E2F repressors and activators coordinate placental development.
Academic Article Canonical and atypical E2Fs regulate the mammalian endocycle.
Academic Article Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.
Academic Article FGFR and PTEN signaling interact during lens development to regulate cell survival.
Academic Article Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice.
Academic Article E2f8 mediates tumor suppression in postnatal liver development.
Academic Article Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
Academic Article Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.
Academic Article Viral oncogene expression in the stem/progenitor cell compartment of the mouse intestine induces adenomatous polyps.
Academic Article A hedgehog pathway-dependent gene signature is associated with poor clinical outcomes in Luminal A breast cancer.
Academic Article NF-?B regulates GDF-15 to suppress macrophage surveillance during early tumor development.
Academic Article hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.
Academic Article Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.
Academic Article Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele.
Academic Article Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.
Academic Article Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis.
Academic Article A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta.
Academic Article The E2F1-3 transcription factors are essential for cellular proliferation.
Academic Article Myc requires distinct E2F activities to induce S phase and apoptosis.
Academic Article E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.
Academic Article Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
Academic Article The reovirus cell attachment protein possesses two independently active trimerization domains: basis of dominant negative effects.
Academic Article RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.
Academic Article Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.
Academic Article Analysis of Cdc6 function in the assembly of mammalian prereplication complexes.
Academic Article Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages.
Academic Article Atypical E2Fs: new players in the E2F transcription factor family.
Academic Article Cited2 is required in trophoblasts for correct placental capillary patterning.
Academic Article Crosstalk between PKCa and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium.
Academic Article Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation.
Academic Article Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression.
Academic Article Biochemical and biophysical characterization of the reovirus cell attachment protein sigma 1: evidence that it is a homotrimer.
Academic Article Trimerization of the reovirus cell attachment protein (sigma 1) induces conformational changes in sigma 1 necessary for its cell-binding function.
Academic Article The N-terminal heptad repeat region of reovirus cell attachment protein sigma 1 is responsible for sigma 1 oligomer stability and possesses intrinsic oligomerization function.
Academic Article The incorporation of reovirus cell attachment protein sigma 1 into virions requires the N-terminal hydrophobic tail and the adjacent heptad repeat region.
Academic Article Conformational and functional analysis of the C-terminal globular head of the reovirus cell attachment protein.
Academic Article The N-terminal quarter of reovirus cell attachment protein sigma 1 possesses intrinsic virion-anchoring function.
Academic Article E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity.
Academic Article Effect of all-trans retinoic acid on procoagulant and fibrinolytic activities of cultured blast cells from patients with acute promyelocytic leukemia.
Academic Article Binding of reovirus to receptor leads to conformational changes in viral capsid proteins that are reversible upon virus detachment.
Academic Article Reovirus protein sigma 1: from cell attachment to protein oligomerization and folding mechanisms.
Academic Article C-terminal trimerization, but not N-terminal trimerization, of the reovirus cell attachment protein Is a posttranslational and Hsp70/ATP-dependent process.
Academic Article Co-translational trimerization of the reovirus cell attachment protein.
Academic Article The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state.
Academic Article Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor.
Academic Article Distinct roles for E2F proteins in cell growth control and apoptosis.
Academic Article Functional analysis of E2F transcription factor.
Academic Article Role of the Rb/E2F pathway in cell growth control.
Academic Article E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2.
Academic Article Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells.
Academic Article Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth.
Academic Article Hypermethylation of GpG islands in the promoter region of p15(INK4b) in acute promyelocytic leukemia represses p15(INK4b) expression and correlates with poor prognosis.
Academic Article Ras enhances Myc protein stability.
Academic Article Tissue-specific targeting of cell fate regulatory genes by E2f factors.
Academic Article Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer.
Academic Article Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase.
Academic Article Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins.
Academic Article Complex transcriptional regulatory mechanisms control expression of the E2F3 locus.
Academic Article Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF-beta1 is a cell cycle-independent effect and influences their hematopoietic potential.
Academic Article Expression of cyclin-dependent kinase inhibitor p15(INK4B) during normal and leukemic myeloid differentiation.
Academic Article High cyclin-dependent kinase inhibitors in Bcl-2 and Bcl-xL-expressing CD34+-proliferating haematopoietic progenitors.
Academic Article Expression of p15(INK4B) in hematopoietic progenitors.
Academic Article Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway.
Academic Article Expression of the c-met proto-oncogene and its ligand, hepatocyte growth factor, in Hodgkin disease.
Academic Article Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death.
Academic Article T-cell apoptosis induced by granulocyte colony-stimulating factor is associated with retinoblastoma protein phosphorylation and reduced expression of cyclin-dependent kinase inhibitors.
Academic Article Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis.
Academic Article Expression of p15(ink4b) gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors.
Academic Article Hsp90 phosphorylation is linked to its chaperoning function. Assembly of the reovirus cell attachment protein.
Academic Article BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia.
Academic Article Evaluating the efficacy of enzalutamide and the development of resistance in a preclinical mouse model of type-I endometrial carcinoma.
Academic Article Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia.
Academic Article Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome.
Academic Article RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
Academic Article Deep learning tools and modeling to estimate the temporal expression of cell cycle proteins from 2D still images.
Academic Article Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner.
Academic Article Discovery of nonautonomous modulators of activated Ras.
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