Regulatory-Associated Protein of mTOR
"Regulatory-Associated Protein of mTOR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adaptor protein component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 that forms stoichiometric complexes with TOR KINASES, which it negatively regulates. It functions as a positive regulator of RIBOSOMAL PROTEIN S6 KINASES.
| Descriptor ID |
D000076223
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| MeSH Number(s) |
D05.500.337.500 D08.811.913.696.620.682.700.931.500.500 D12.644.360.024.324 D12.776.157.057.157 D12.776.476.024.419 D12.776.476.925.500.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Regulatory-Associated Protein of mTOR".
Below are MeSH descriptors whose meaning is more specific than "Regulatory-Associated Protein of mTOR".
This graph shows the total number of publications written about "Regulatory-Associated Protein of mTOR" by people in this website by year, and whether "Regulatory-Associated Protein of mTOR" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Regulatory-Associated Protein of mTOR" by people in Profiles.
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Gan W, Dai X, Dai X, Xie J, Yin S, Zhu J, Wang C, Liu Y, Guo J, Wang M, Liu J, Hu J, Quinton RJ, Ganem NJ, Liu P, Asara JM, Pandolfi PP, Yang Y, He Z, Gao G, Wei W. LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. Nat Cell Biol. 2020 02; 22(2):246-256.
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Sundin T, Peffley DM, Hentosh P. Disruption of an hTERT-mTOR-RAPTOR protein complex by a phytochemical perillyl alcohol and rapamycin. Mol Cell Biochem. 2013 Mar; 375(1-2):97-104.