Liver X Receptors

"Liver X Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Nuclear receptors that bind OXYSTEROLS and function as heterodimers with RETINOID X RECEPTORS. They have important functions in regulating cholesterol homeostasis, ENERGY METABOLISM; INFLAMMATION; and the immune response.

Descriptor ID	D000071518
MeSH Number(s)	D12.776.260.531 D12.776.826.194
Concept/Terms	Liver X Receptors Liver X Receptors Nuclear Oxysterol Receptors Oxysterol Receptors, Nuclear Liver X Receptor Liver X Receptor Alpha Liver X Receptor Alpha Liver X Receptor-Alpha NR1H3 Protein LXRalpha Protein Nuclear Orphan Receptor LXR-Alpha Nuclear Orphan Receptor LXR Alpha Oxysterols Receptor LXR-Alpha LXR-Alpha, Oxysterols Receptor Oxysterols Receptor LXR Alpha Nuclear Receptor Subfamily 1, Group H, Member 3 LXR-Alpha Protein LXR Alpha Protein Liver X Receptor Beta Liver X Receptor Beta Liver X Receptor-Beta Nuclear Receptor Subfamily 1, Group H, Member 2 Oxysterols Receptor LXR-Beta LXR-Beta, Oxysterols Receptor Oxysterols Receptor LXR Beta LXRbeta Protein NR1H2 Protein

Below are MeSH descriptors whose meaning is more general than "Liver X Receptors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Liver X Receptors [D12.776.260.531]
Receptors, Cytoplasmic and Nuclear [D12.776.826]
Liver X Receptors [D12.776.826.194]

Below are MeSH descriptors whose meaning is related to "Liver X Receptors".

Below are MeSH descriptors whose meaning is more specific than "Liver X Receptors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Liver X Receptors" by people in this website by year, and whether "Liver X Receptors" was a major or minor topic of these publications.

Bar chart showing 8 publications over 8 distinct years, with a maximum of 1 publications in 2004 and 2009 and 2010 and 2011 and 2012 and 2016 and 2018 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	0	1	1
2009	0	1	1
2010	0	1	1
2011	0	1	1
2012	0	1	1
2016	1	0	1
2018	1	0	1
2019	0	1	1

Below are the most recent publications written about "Liver X Receptors" by people in Profiles.

Xu Y, Xu Y, Zhu Y, Sun H, Juguilon C, Li F, Fan D, Yin L, Zhang Y. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020 01 08; 28(1):202-216.

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DeLeon-Pennell KY, Mouton AJ, Ero OK, Ma Y, Padmanabhan Iyer R, Flynn ER, Espinoza I, Musani SK, Vasan RS, Hall ME, Fox ER, Lindsey ML. LXR/RXR signaling and neutrophil phenotype following myocardial infarction classify sex differences in remodeling. Basic Res Cardiol. 2018 08 21; 113(5):40.

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Kurowska-Stolarska M, Hasoo MK, Welsh DJ, Stewart L, McIntyre D, Morton BE, Johnstone S, Miller AM, Asquith DL, Millar NL, Millar AB, Feghali-Bostwick CA, Hirani N, Crick PJ, Wang Y, Griffiths WJ, McInnes IB, McSharry C. The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis. J Allergy Clin Immunol. 2017 Jun; 139(6):1946-1956.

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He YQ, Ma GY, Peng JN, Ma ZY, Hamann MT. Liver X receptor and peroxisome proliferator-activated receptor agonist from Cornus alternifolia. Biochim Biophys Acta. 2012 Jul; 1820(7):1021-6.

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Loane DJ, Washington PM, Vardanian L, Pocivavsek A, Hoe HS, Duff KE, Cernak I, Rebeck GW, Faden AI, Burns MP. Modulation of ABCA1 by an LXR agonist reduces ß-amyloid levels and improves outcome after traumatic brain injury. J Neurotrauma. 2011 Feb; 28(2):225-36.

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Fujimoto VY, Kane JP, Ishida BY, Bloom MS, Browne RW. High-density lipoprotein metabolism and the human embryo. Hum Reprod Update. 2010 Jan-Feb; 16(1):20-38.

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Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, Glass CK. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009 Mar 15; 23(6):681-93.

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Brown J, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B. Differential expression of cholesterol hydroxylases in Alzheimer's disease. J Biol Chem. 2004 Aug 13; 279(33):34674-81.

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