Origin Recognition Complex
"Origin Recognition Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The origin recognition complex is a multi-subunit DNA-binding protein that initiates DNA REPLICATION in eukaryotes.
Descriptor ID |
D051738
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MeSH Number(s) |
D12.776.260.640
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Origin Recognition Complex".
Below are MeSH descriptors whose meaning is more specific than "Origin Recognition Complex".
This graph shows the total number of publications written about "Origin Recognition Complex" by people in this website by year, and whether "Origin Recognition Complex" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Origin Recognition Complex" by people in Profiles.
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Endoreduplication of the mouse genome in the absence of ORC1. Genes Dev. 2018 07 01; 32(13-14):978-990.
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Reconstitution of R6K DNA replication in vitro using 22 purified proteins. J Biol Chem. 2003 Nov 14; 278(46):45476-84.
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Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor. Mol Cell Biol. 1996 Dec; 16(12):6977-84.