"I-kappa B Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
| Descriptor ID |
D020672
|
| MeSH Number(s) |
D12.644.360.365 D12.776.260.420 D12.776.476.381 D12.776.930.326
|
| Concept/Terms |
I-kappa B Proteins- I-kappa B Proteins
- I kappa B Proteins
- I kappa B
- IkB DNA-Binding Proteins
- IkB DNA Binding Proteins
- I-kappa B
|
Below are MeSH descriptors whose meaning is more general than "I-kappa B Proteins".
Below are MeSH descriptors whose meaning is more specific than "I-kappa B Proteins".
This graph shows the total number of publications written about "I-kappa B Proteins" by people in this website by year, and whether "I-kappa B Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 |
| 2000 | 2 | 2 | 4 |
| 2001 | 3 | 2 | 5 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 6 | 6 |
| 2005 | 1 | 2 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 2 | 3 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 3 | 3 |
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Below are the most recent publications written about "I-kappa B Proteins" by people in Profiles.
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TNFR1 delivers pro-survival signals that are required for limiting TNFR2-dependent activation-induced cell death (AICD) in CD8+ T cells. Eur J Immunol. 2011 Feb; 41(2):335-44.
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Postinjury estrogen treatment of chronic spinal cord injury improves locomotor function in rats. J Neurosci Res. 2010 Jun; 88(8):1738-50.
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Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I. Arterioscler Thromb Vasc Biol. 2010 Apr; 30(4):766-72.
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NF-kappaB functions in stromal fibroblasts to regulate early postnatal muscle development. J Biol Chem. 2010 Feb 19; 285(8):5479-87.
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A novel role for IkappaBzeta in the regulation of IFNgamma production. PLoS One. 2009 Aug 26; 4(8):e6776.
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Beta3 integrin-mediated ubiquitination activates survival signaling during myocardial hypertrophy. FASEB J. 2009 Aug; 23(8):2759-71.
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Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation. J Immunol. 2007 Nov 15; 179(10):7121-7.
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Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappaB activation. Arterioscler Thromb Vasc Biol. 2007 Oct; 27(10):2184-90.
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Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells. Apoptosis. 2007 Apr; 12(4):671-84.
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Nephritogenic anti-DNA antibodies regulate gene expression in MRL/lpr mouse glomerular mesangial cells. Arthritis Rheum. 2006 Jul; 54(7):2198-210.