Methyl-CpG-Binding Protein 2
"Methyl-CpG-Binding Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-binding protein that interacts with methylated CPG ISLANDS. It plays a role in repressing GENETIC TRANSCRIPTION and is frequently mutated in RETT SYNDROME.
| Descriptor ID |
D051783
|
| MeSH Number(s) |
D12.776.260.536 D12.776.660.235.550 D12.776.664.235.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Methyl-CpG-Binding Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Methyl-CpG-Binding Protein 2".
This graph shows the total number of publications written about "Methyl-CpG-Binding Protein 2" by people in this website by year, and whether "Methyl-CpG-Binding Protein 2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Methyl-CpG-Binding Protein 2" by people in Profiles.
-
Binding Analysis of Methyl-CpG Binding Domain of MeCP2 and Rett Syndrome Mutations. ACS Chem Biol. 2016 10 21; 11(10):2706-2715.
-
Impact of Rett Syndrome Mutations on MeCP2 MBD Stability. Biochemistry. 2015 Oct 20; 54(41):6357-68.
-
Structural, Dynamical, and Energetical Consequences of Rett Syndrome Mutation R133C in MeCP2. Comput Math Methods Med. 2015; 2015:746157.
-
Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups. Ann Rheum Dis. 2013 Mar; 72(3):437-44.
-
The many faces of MeCP2. Neuropsychopharmacology. 2012 Jan; 37(2):313-4.
-
Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus. Arthritis Rheum. 2009 Apr; 60(4):1076-84.
-
Common variants within MECP2 confer risk of systemic lupus erythematosus. PLoS One. 2008 Mar 05; 3(3):e1727.
-
Finding new etiologies of mental retardation and hypotonia: X marks the spot. Dev Med Child Neurol. 2008 Feb; 50(2):104-11.