Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome.

Descriptor ID	D000072233
MeSH Number(s)	D12.776.476.024.381
Concept/Terms	Homer Scaffolding Proteins Homer Scaffolding Proteins Proteins, Homer Scaffolding Scaffolding Proteins, Homer Homer Proteins Proteins, Homer Homer 1C Homer 1C Homer 1C Proteins Proteins, Homer 1C Homer 3 Homer 3 Homer 3 Proteins Proteins, Homer 3 Homer 2 Homer 2 Homer 2 Proteins Proteins, Homer 2 Homer 1 Homer 1 Homer 1a Homer 1a Homer 1 Proteins Proteins, Homer 1

Below are MeSH descriptors whose meaning is more general than "Homer Scaffolding Proteins".

Below are MeSH descriptors whose meaning is related to "Homer Scaffolding Proteins".

Below are MeSH descriptors whose meaning is more specific than "Homer Scaffolding Proteins".