"Caspase 9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
Descriptor ID |
D053453
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MeSH Number(s) |
D08.811.277.656.262.500.126.550.900 D08.811.277.656.300.200.126.550.900 D12.644.360.024.131.155 D12.644.360.075.358.155 D12.644.360.075.405.550.900 D12.776.157.057.006.155 D12.776.476.024.139.155 D12.776.476.075.358.155 D12.776.476.075.405.550.900
|
Concept/Terms |
Caspase 9- Caspase 9
- ICE-Like Apoptotic Protease 6
- ICE Like Apoptotic Protease 6
- Apoptotic Protease Activating Factor 3
- ICE-LAP6 Protein
- ICE LAP6 Protein
- Caspase-9
Procaspase-9- Procaspase-9
- Procaspase 9
- Pro-Caspase-9
- Pro Caspase 9
|
Below are MeSH descriptors whose meaning is more general than "Caspase 9".
Below are MeSH descriptors whose meaning is more specific than "Caspase 9".
This graph shows the total number of publications written about "Caspase 9" by people in this website by year, and whether "Caspase 9" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 2 | 2 |
2000 | 0 | 1 | 1 |
2001 | 0 | 3 | 3 |
2002 | 0 | 3 | 3 |
2003 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2009 | 0 | 3 | 3 |
2011 | 0 | 2 | 2 |
2012 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2014 | 0 | 2 | 2 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Caspase 9" by people in Profiles.
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Key apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects. Eur J Hum Genet. 2018 03; 26(3):420-427.
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Induction of apoptosis in human glioma cell lines of various grades through the ROS-mediated mitochondrial pathway and caspase activation by Rhaponticum carthamoides transformed root extract. Mol Cell Biochem. 2018 Aug; 445(1-2):89-97.
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Irisin promotes human umbilical vein endothelial cell proliferation through the ERK signaling pathway and partly suppresses high glucose-induced apoptosis. PLoS One. 2014; 9(10):e110273.
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Receptor-interacting protein kinases modulate noise-induced sensory hair cell death. Cell Death Dis. 2014 May 29; 5:e1262.
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Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation. Int J Oncol. 2013 Dec; 43(6):2064-72.
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Electrochemical control of cell death by reduction-induced intrinsic apoptosis and oxidation-induced necrosis on CoCrMo alloy in vitro. Biomaterials. 2012 Sep; 33(27):6295-304.
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Valproic acid induced differentiation and potentiated efficacy of taxol and nanotaxol for controlling growth of human glioblastoma LN18 and T98G cells. Neurochem Res. 2011 Dec; 36(12):2292-305.
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Neuroprotective effects of genistein in VSC4.1 motoneurons exposed to activated microglial cytokines. Neurochem Int. 2011 Aug; 59(2):175-84.
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Combination of taxol and Bcl-2 siRNA induces apoptosis in human glioblastoma cells and inhibits invasion, angiogenesis and tumour growth. J Cell Mol Med. 2009 Oct; 13(10):4205-18.
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Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms. Mol Pharmacol. 2009 Aug; 76(2):342-55.