"A Kinase Anchor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA.
| Descriptor ID |
D054758
|
| MeSH Number(s) |
D12.644.360.024.065 D12.776.157.057.003 D12.776.476.024.069
|
| Concept/Terms |
A Kinase Anchor Proteins- A Kinase Anchor Proteins
- Protein Kinase A Anchor Proteins
- A-Kinase Anchor Proteins
- Anchor Proteins, A-Kinase
|
Below are MeSH descriptors whose meaning is more general than "A Kinase Anchor Proteins".
Below are MeSH descriptors whose meaning is more specific than "A Kinase Anchor Proteins".
This graph shows the total number of publications written about "A Kinase Anchor Proteins" by people in this website by year, and whether "A Kinase Anchor Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "A Kinase Anchor Proteins" by people in Profiles.
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Wang L, Burmeister BT, Johnson KR, Baillie GS, Karginov AV, Skidgel RA, O'Bryan JP, Carnegie GK. UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy. Cell Signal. 2015 May; 27(5):908-22.
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Logue MW, Schu M, Vardarajan BN, Farrell J, Bennett DA, Buxbaum JD, Byrd GS, Ertekin-Taner N, Evans D, Foroud T, Goate A, Graff-Radford NR, Kamboh MI, Kukull WA, Manly JJ. Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans. Alzheimers Dement. 2014 Nov; 10(6):609-618.e11.
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Reissner KJ, Uys JD, Schwacke JH, Comte-Walters S, Rutherford-Bethard JL, Dunn TE, Blumer JB, Schey KL, Kalivas PW. AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis. J Neurosci. 2011 Apr 13; 31(15):5648-58.
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Xu M, Woodward JJ. Ethanol inhibition of NMDA receptors under conditions of altered protein kinase A activity. J Neurochem. 2006 Mar; 96(6):1760-7.