Tumor Suppressor p53-Binding Protein 1
"Tumor Suppressor p53-Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. It plays a critical role in the cellular response to DNA DAMAGE and localizes to DOUBLE-STRAND DNA BREAKS. It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation.
|Tumor Suppressor p53-Binding Protein 1
- Tumor Suppressor p53-Binding Protein 1
- Tumor Suppressor p53 Binding Protein 1
- TP53BP1 Protein
- p202 Protein
- Tumor Protein p53-Binding Protein, 1
- Tumor Protein p53 Binding Protein, 1
- 53BP1 Protein
Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor p53-Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Tumor Suppressor p53-Binding Protein 1".
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Below are the most recent publications written about "Tumor Suppressor p53-Binding Protein 1" by people in Profiles.
Lou J, Priest DG, Solano A, Kerjouan A, Hinde E. Spatiotemporal dynamics of 53BP1 dimer recruitment to a DNA double strand break. Nat Commun. 2020 11 13; 11(1):5776.
Zhang J, Lee YR, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discov. 2019 09; 9(9):1306-1323.