TCF Transcription Factors
"TCF Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.
| Descriptor ID |
D051820
|
| MeSH Number(s) |
D12.776.260.730 D12.776.660.235.400.800 D12.776.664.235.400.800 D12.776.930.875
|
| Concept/Terms |
TCF Transcription Factors- TCF Transcription Factors
- Transcription Factors, TCF
- Lymphoid Enhancer Factors
- T-Cell Factors
- T Cell Factors
- LEF Transcription Factors
- Transcription Factors, LEF
|
Below are MeSH descriptors whose meaning is more general than "TCF Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "TCF Transcription Factors".
This graph shows the total number of publications written about "TCF Transcription Factors" by people in this website by year, and whether "TCF Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "TCF Transcription Factors" by people in Profiles.
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Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC. Carcinogenesis. 2013 Feb; 34(2):277-86.
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Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans. Diabetes. 2007 Feb; 56(2):389-93.
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Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women. Diabetes. 2006 Dec; 55(12):3630-4.
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Cleavage of beta-catenin by calpain in prostate and mammary tumor cells. Cancer Res. 2004 Oct 15; 64(20):7237-40.
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Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription. J Cell Biol. 2001 Jan 08; 152(1):87-96.