"Toll-Like Receptor 9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that binds unmethylated CPG CLUSTERS. It mediates cellular responses to bacterial pathogens by distinguishing between self and bacterial DNA.
| Descriptor ID |
D051217
|
| MeSH Number(s) |
D12.776.260.750 D12.776.543.750.705.910.500.900
|
| Concept/Terms |
Toll-Like Receptor 9- Toll-Like Receptor 9
- Toll Like Receptor 9
- TLR9 Receptor
- Receptor, TLR9
- TLR9 Protein
- CD289 Antigen
- Antigen, CD289
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 9".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 9".
This graph shows the total number of publications written about "Toll-Like Receptor 9" by people in this website by year, and whether "Toll-Like Receptor 9" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2018 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Toll-Like Receptor 9" by people in Profiles.
-
The TLR7/8/9 Antagonist IMO-8503 Inhibits Cancer-Induced Cachexia. Cancer Res. 2018 12 01; 78(23):6680-6690.
-
Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans. Nat Immunol. 2018 06; 19(6):571-582.
-
Estrogen Receptor a Deficiency Modulates TLR Ligand-Mediated PDC-TREM Expression in Plasmacytoid Dendritic Cells in Lupus-Prone Mice. J Immunol. 2015 Dec 15; 195(12):5561-71.
-
Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94. J Med Chem. 2015 May 14; 58(9):3922-43.
-
Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. Vaccine. 2014 May 19; 32(24):2882-95.
-
Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone. Nat Commun. 2010 Sep 21; 1:79.
-
Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood. Hum Immunol. 2009 Oct; 70(10):777-84.
-
TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes. J Immunol. 2009 Jul 15; 183(2):1144-54.
-
A role for Fli-1 in B cell proliferation: implications for SLE pathogenesis. Clin Immunol. 2008 Oct; 129(1):19-30.
-
Modulation of autoimmunity by TLR9 in the chronic graft-vs-host model of systemic lupus erythematosus. J Immunol. 2006 Nov 15; 177(10):7444-50.