"NLR Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular signaling proteins that are defined by the presence of a NUCLEOTIDE-binding region and LEUCINE-rich repeats. Their general structure consists of any of a variety of effector domains at their N-termini such as a caspase recruitment domain (CARD), a central nucleotide-binding domain, and a variable number of C-terminal leucine-rich repeats. They are important for pathogen recognition in the INNATE IMMUNE RESPONSE of animals and plants. Members of the NLR protein family include the NOD SIGNALING ADAPTOR PROTEINS.
| Descriptor ID |
D000070576
|
| MeSH Number(s) |
D12.644.360.539
|
| Concept/Terms |
NLR Proteins- NLR Proteins
- Proteins, NLR
- NLR Protein
- Protein, NLR
- NOD-like Receptors
- NOD like Receptors
- Receptors, NOD-like
- Nucleotide-binding Domain Leucine-rich Repeat Proteins
- Nucleotide binding Domain Leucine rich Repeat Proteins
|
Below are MeSH descriptors whose meaning is more general than "NLR Proteins".
Below are MeSH descriptors whose meaning is more specific than "NLR Proteins".
This graph shows the total number of publications written about "NLR Proteins" by people in this website by year, and whether "NLR Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "NLR Proteins" by people in Profiles.
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Targeting inflammasome/IL-1 pathways for cancer immunotherapy. Sci Rep. 2016 10 27; 6:36107.