"Guanylate Cyclase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.
| Descriptor ID |
D006162
|
| MeSH Number(s) |
D08.811.520.650.600 D12.644.360.350 D12.776.476.350
|
| Concept/Terms |
Guanylate Cyclase- Guanylate Cyclase
- Cyclase, Guanylate
- Guanyl Cyclase
- Cyclase, Guanyl
- Guanylyl Cyclase
- Cyclase, Guanylyl
- Inosinate Cyclase
- Cyclase, Inosinate
- Deoxyguanylate Cyclase
- Cyclase, Deoxyguanylate
|
Below are MeSH descriptors whose meaning is more general than "Guanylate Cyclase".
Below are MeSH descriptors whose meaning is more specific than "Guanylate Cyclase".
This graph shows the total number of publications written about "Guanylate Cyclase" by people in this website by year, and whether "Guanylate Cyclase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2011 | 1 | 1 | 2 |
| 2015 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanylate Cyclase" by people in Profiles.
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Effect of Praliciguat on Peak Rate of Oxygen Consumption in Patients With Heart Failure With Preserved Ejection Fraction: The CAPACITY HFpEF Randomized Clinical Trial. JAMA. 2020 10 20; 324(15):1522-1531.
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S-Nitrosylation in Regulation of Inflammation and Cell Damage. Curr Drug Targets. 2018; 19(15):1831-1838.
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Reduced vascular responses to soluble guanylyl cyclase but increased sensitivity to sildenafil in female rats with type 2 diabetes. Am J Physiol Heart Circ Physiol. 2015 Jul 15; 309(2):H297-304.
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Riociguat: a novel new drug for treatment of pulmonary hypertension. Pharmacotherapy. 2015 May; 35(5):502-19.
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Generation, translocation, and action of nitric oxide in living systems. Chem Biol. 2011 Oct 28; 18(10):1211-20.
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Assessment of the effects of renal impairment on the pharmacokinetics of the soluble guanylate cyclase activator cinaciguat after a single intravenous dose. J Clin Pharmacol. 2012 Aug; 52(8):1240-7.
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Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal. J Neurosci. 2008 Apr 09; 28(15):4008-14.
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Ontogeny of atrial natriuretic peptide and its receptor in the lung: effects on perinatal surfactant release. Pediatr Res. 2008 Mar; 63(3):239-44.
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Nitric oxide inactivates the retinoblastoma pathway in chronic inflammation. Cancer Res. 2007 Oct 01; 67(19):9286-93.
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Turning cones off: the role of the 9-methyl group of retinal in red cones. J Gen Physiol. 2006 Dec; 128(6):671-85.