| Item Type | Name |
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Concept
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src Homology Domains
|
|
Concept
|
rev Gene Products, Human Immunodeficiency Virus
|
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Concept
|
Basic Helix-Loop-Helix Transcription Factors
|
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Concept
|
DNA Methylation
|
|
Concept
|
Genes, env
|
|
Concept
|
Regulon
|
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Concept
|
Vibrio parahaemolyticus
|
|
Concept
|
HeLa Cells
|
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Concept
|
Arabidopsis
|
|
Concept
|
Oncogenes
|
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Concept
|
Cell Nucleus
|
|
Concept
|
Gene Expression
|
|
Concept
|
Drosophila melanogaster
|
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Concept
|
RNA Interference
|
|
Concept
|
Fluorescent Dyes
|
|
Concept
|
Genes, tat
|
|
Concept
|
Fluorescence Polarization Immunoassay
|
|
Concept
|
Fund Raising
|
|
Concept
|
Micelles
|
|
Concept
|
GTP-Binding Proteins
|
|
Concept
|
HIV-1
|
|
Concept
|
Keto Acids
|
|
Concept
|
Human Immunodeficiency Virus Proteins
|
|
Concept
|
Transcription Initiation Site
|
|
Concept
|
Molecular Biology
|
|
Concept
|
Exoribonucleases
|
|
Concept
|
Genetic Complementation Test
|
|
Concept
|
Computer Simulation
|
|
Concept
|
RNA-Induced Silencing Complex
|
|
Concept
|
Chromosomal Proteins, Non-Histone
|
|
Concept
|
Trans-Activators
|
|
Concept
|
Adenosine Triphosphate
|
|
Concept
|
Protein Biosynthesis
|
|
Concept
|
Molecular Dynamics Simulation
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Algorithms
|
|
Concept
|
Antineoplastic Agents
|
|
Concept
|
Cytochrome P-450 Enzyme System
|
|
Concept
|
Cytidine Deaminase
|
|
Concept
|
Methylococcus capsulatus
|
|
Concept
|
Butyrates
|
|
Concept
|
Protein Interaction Domains and Motifs
|
|
Concept
|
Endoribonucleases
|
|
Concept
|
Cytoplasmic Structures
|
|
Concept
|
Poxviridae
|
|
Concept
|
Cytosine Deaminase
|
|
Concept
|
Chromatin
|
|
Concept
|
Flavins
|
|
Concept
|
Cholic Acids
|
|
Concept
|
Cell Line, Transformed
|
|
Concept
|
Nucleosomes
|
|
Concept
|
vpr Gene Products, Human Immunodeficiency Virus
|
|
Concept
|
Drug Evaluation, Preclinical
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
Static Electricity
|
|
Concept
|
Histone Deacetylases
|
|
Concept
|
Dimerization
|
|
Concept
|
HIV Infections
|
|
Concept
|
Repressor Proteins
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
Cytoplasm
|
|
Concept
|
Drosophila
|
|
Concept
|
Jurkat Cells
|
|
Concept
|
Hot Temperature
|
|
Concept
|
DNA, Bacterial
|
|
Concept
|
Escherichia coli
|
|
Concept
|
CCAAT-Binding Factor
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Genes, rev
|
|
Concept
|
5' Untranslated Regions
|
|
Concept
|
Vero Cells
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Vaccinia virus
|
|
Concept
|
Crystallography
|
|
Concept
|
Catalytic Domain
|
|
Concept
|
DNA Damage
|
|
Concept
|
Core Binding Factor Alpha 2 Subunit
|
|
Concept
|
Cytoplasmic Granules
|
|
Concept
|
Crystallography, X-Ray
|
|
Concept
|
Escherichia coli Proteins
|
|
Concept
|
nef Gene Products, Human Immunodeficiency Virus
|
|
Concept
|
Systems Biology
|
|
Concept
|
Sirtuins
|
|
Concept
|
Oxalates
|
|
Concept
|
Flavin-Adenine Dinucleotide
|
|
Concept
|
NAD
|
|
Concept
|
Carbon Isotopes
|
|
Concept
|
CD4-Positive T-Lymphocytes
|
|
Concept
|
Small Ubiquitin-Related Modifier Proteins
|
|
Concept
|
Sequence Homology, Amino Acid
|
|
Concept
|
Interleukin-6
|
|
Concept
|
Staining and Labeling
|
|
Concept
|
In Situ Hybridization
|
|
Concept
|
Cell Line
|
|
Concept
|
Adenosine Triphosphatases
|
|
Concept
|
Coronavirus Infections
|
|
Concept
|
Heterochromatin
|
|
Concept
|
DNA Repair
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
vif Gene Products, Human Immunodeficiency Virus
|
|
Concept
|
Hydrogen Bonding
|
|
Concept
|
Base Sequence
|
|
Concept
|
Amino Acid Motifs
|
|
Concept
|
HIV
|
|
Concept
|
Chromatin Assembly and Disassembly
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
Molecular Sequence Data
|
|
Concept
|
Ribosomes
|
|
Academic Article
|
Broadband 13C-13C adiabatic mixing in solution optimized for high fields.
|
|
Academic Article
|
Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
|
|
Academic Article
|
The mRNA cap-binding protein eIF4E in post-transcriptional gene expression.
|
|
Academic Article
|
NMR structure of the flavin domain from soluble methane monooxygenase reductase from Methylococcus capsulatus (Bath).
|
|
Academic Article
|
A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada.
|
|
Academic Article
|
Folding transitions during assembly of the eukaryotic mRNA cap-binding complex.
|
|
Academic Article
|
Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.
|
|
Academic Article
|
The structural basis of yeast prion strain variants.
|
|
Academic Article
|
mRNA decapping is promoted by an RNA-binding channel in Dcp2.
|
|
Academic Article
|
Decreased recognition of SUMO-sensitive target genes following modification of SF-1 (NR5A1).
|
|
Academic Article
|
Control of mRNA decapping by Dcp2: An open and shut case?
|
|
Academic Article
|
Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine.
|
|
Academic Article
|
A kinetic assay to monitor RNA decapping under single- turnover conditions.
|
|
Academic Article
|
SRP RNA controls a conformational switch regulating the SRP-SRP receptor interaction.
|
|
Academic Article
|
An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model.
|
|
Academic Article
|
Backbone and sidechain methyl Ile (delta1), Leu and Val resonance assignments of the catalytic domain of the yeast mRNA decapping enzyme, Dcp2.
|
|
Academic Article
|
Identification and analysis of the interaction between Edc3 and Dcp2 in Saccharomyces cerevisiae.
|
|
Academic Article
|
Cricket paralysis virus antagonizes Argonaute 2 to modulate antiviral defense in Drosophila.
|
|
Academic Article
|
A split active site couples cap recognition by Dcp2 to activation.
|
|
Academic Article
|
The crystal structure Escherichia coli Spy.
|
|
Academic Article
|
Dcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition.
|
|
Academic Article
|
Vif hijacks CBF-? to degrade APOBEC3G and promote HIV-1 infection.
|
|
Academic Article
|
Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan.
|
|
Academic Article
|
The crystal structure of the periplasmic domain of Vibrio parahaemolyticus CpxA.
|
|
Academic Article
|
In support of the BMRB.
|
|
Academic Article
|
Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G.
|
|
Academic Article
|
CBF? stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression.
|
|
Academic Article
|
From systems to structure: bridging networks and mechanism.
|
|
Academic Article
|
Judge, jury, and executioner: DXO functions as a decapping enzyme and exoribonuclease in pre-mRNA quality control.
|
|
Academic Article
|
The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals.
|
|
Academic Article
|
Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme Dcp2.
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|
Academic Article
|
A mutually assured destruction mechanism attenuates light signaling in Arabidopsis.
|
|
Academic Article
|
Lineage-Specific Viral Hijacking of Non-canonical E3?Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity.
|
|
Academic Article
|
Thermodynamics of Rev-RNA interactions in HIV-1 Rev-RRE assembly.
|
|
Academic Article
|
Two-headed tetraphosphate cap analogs are inhibitors of the Dcp1/2 RNA decapping complex.
|
|
Academic Article
|
Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
|
|
Academic Article
|
Molecular biology: Messenger RNAs marked for longer life.
|
|
Academic Article
|
Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler.
|
|
Academic Article
|
CBF? and HIV Infection.
|
|
Academic Article
|
Biochemical Basis for Distinct Roles of the Heterochromatin Proteins Swi6 and Chp2.
|
|
Academic Article
|
Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription.
|
|
Academic Article
|
Application of a Schizosaccharomyces pombe Edc1-fused Dcp1-Dcp2 decapping enzyme for transcription start site mapping.
|
|
Academic Article
|
Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors.
|
|
Academic Article
|
Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis.
|
|
Academic Article
|
Control of mRNA decapping by autoinhibition.
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|
Academic Article
|
CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.
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|
Academic Article
|
A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability.
|
|
Academic Article
|
Decapping enzymes STOP "cancer" ribosomes in their tracks.
|
|
Academic Article
|
Structural and molecular mechanisms for the control of eukaryotic 5'-3' mRNA decay.
|
|
Academic Article
|
Publisher Correction: Structural and molecular mechanisms for the control of eukaryotic 5'-3' mRNA decay.
|
|
Academic Article
|
Conformational Dynamics of the HIV-Vif Protein Complex.
|
|
Academic Article
|
ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.
|
|
Academic Article
|
Pat1 activates late steps in mRNA decay by multiple mechanisms.
|
|
Academic Article
|
Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism.
|
|
Academic Article
|
A sensitive and robust method for obtaining intermolecular NOEs between side chains in large protein complexes.
|
|
Academic Article
|
Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect.
|
|
Academic Article
|
Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation.
|
|
Academic Article
|
Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes.
|
|
Academic Article
|
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
|
|
Academic Article
|
Biophysical Properties of HP1-Mediated Heterochromatin.
|
|
Academic Article
|
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing.
|
|
Academic Article
|
Pdc2/Pat1 increases the range of decay factors and RNA bound by the Lsm1-7 complex.
|
|
Concept
|
Molecular Sequence Annotation
|
|
Concept
|
Drug Repositioning
|
|
Concept
|
Pandemics
|
|
Concept
|
Argonaute Proteins
|
|
Concept
|
Protein Conformation, alpha-Helical
|
|
Concept
|
Suppressor of Cytokine Signaling 3 Protein
|
|
Concept
|
APOBEC Deaminases
|
|
Concept
|
APOBEC-3G Deaminase
|
|
Concept
|
Protein Domains
|
|
Concept
|
Elongin
|
|
Concept
|
NEDD8 Protein
|
|
Concept
|
HEK293 Cells
|
|
Academic Article
|
Characterization of an A3G-VifHIV-1-CRL5-CBF? Structure Using a Cross-linking Mass Spectrometry Pipeline for Integrative Modeling of Host-Pathogen Complexes.
|
|
Academic Article
|
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
|
|
Academic Article
|
Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis.
|
|
Academic Article
|
Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9.
|
|
Academic Article
|
The structural basis for HIV-1 Vif antagonism of human APOBEC3G.
|
|
Academic Article
|
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
|
|
Academic Article
|
A call to order: Examining structured domains in biomolecular condensates.
|