"DNA Cleavage" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A reaction that severs one of the covalent sugar-phosphate linkages between NUCLEOTIDES that compose the sugar phosphate backbone of DNA. It is catalyzed enzymatically, chemically or by radiation. Cleavage may be exonucleolytic - removing the end nucleotide, or endonucleolytic - splitting the strand in two.
| Descriptor ID |
D053837
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| MeSH Number(s) |
G02.111.210 G05.193
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "DNA Cleavage".
Below are MeSH descriptors whose meaning is more specific than "DNA Cleavage".
This graph shows the total number of publications written about "DNA Cleavage" by people in this website by year, and whether "DNA Cleavage" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 1 | 2 |
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Below are the most recent publications written about "DNA Cleavage" by people in Profiles.
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Analysis of diazofluorene DNA binding and damaging activity: DNA cleavage by a synthetic monomeric diazofluorene. Angew Chem Int Ed Engl. 2014 Aug 25; 53(35):9325-8.
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XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4. Mol Cell. 2014 May 08; 54(3):460-71.