"Genomic Instability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.
Descriptor ID |
D042822
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MeSH Number(s) |
C23.550.362 G05.365.590.335 G05.370
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Concept/Terms |
Genomic Instability- Genomic Instability
- Genomic Instabilities
- Instabilities, Genomic
- Instability, Genomic
- Genome Instability
- Genome Instabilities
- Instabilities, Genome
- Instability, Genome
Genomic Stability- Genomic Stability
- Genomic Stabilities
- Stabilities, Genomic
- Stability, Genomic
- Genome Stability
- Genome Stabilities
- Stabilities, Genome
- Stability, Genome
|
Below are MeSH descriptors whose meaning is more general than "Genomic Instability".
Below are MeSH descriptors whose meaning is more specific than "Genomic Instability".
This graph shows the total number of publications written about "Genomic Instability" by people in this website by year, and whether "Genomic Instability" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 1 | 2 |
2006 | 1 | 2 | 3 |
2009 | 1 | 0 | 1 |
2010 | 2 | 1 | 3 |
2011 | 2 | 0 | 2 |
2013 | 0 | 1 | 1 |
2015 | 1 | 2 | 3 |
2016 | 2 | 1 | 3 |
2017 | 1 | 1 | 2 |
2018 | 1 | 2 | 3 |
2019 | 1 | 0 | 1 |
2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Genomic Instability" by people in Profiles.
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Clinical utility of chromosomal microarray in establishing clonality and high risk features in patients with Richter transformation. Cancer Genet. 2022 01; 260-261:18-22.
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Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrity. Life Sci Alliance. 2021 09; 4(9).
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Transcription fidelity: New paradigms in epigenetic inheritance, genome instability and disease. DNA Repair (Amst). 2019 09; 81:102652.
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Stromal PTEN determines mammary epithelial response to radiotherapy. Nat Commun. 2018 07 17; 9(1):2783.
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A critical role for nucleoporin 358 (Nup358) in transposon silencing and piRNA biogenesis in Drosophila. J Biol Chem. 2018 06 15; 293(24):9140-9147.
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DNA Mismatch Repair Deficiency Promotes Genomic Instability in a Subset of Papillary Thyroid Cancers. World J Surg. 2018 02; 42(2):358-366.
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Inherited mitochondrial genomic instability and chemical exposures. Toxicology. 2017 11 01; 391:75-83.
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Co-chaperone Hsp70/Hsp90-organizing protein (Hop) is required for transposon silencing and Piwi-interacting RNA (piRNA) biogenesis. J Biol Chem. 2017 04 14; 292(15):6039-6046.
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Analysis of pCERC7, a small antibiotic resistance plasmid from a commensal ST131 Escherichia coli, defines a diverse group of plasmids that include various segments adjacent to a multimer resolution site and encode the same NikA relaxase accessory protein enabling mobilisation. Plasmid. 2017 01; 89:42-48.
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Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing. Nat Cell Biol. 2016 07; 18(7):777-89.