CCCTC-Binding Factor

"CCCTC-Binding Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A repressor protein with poly(ADP)-ribose binding activity that binds CHROMATIN and DNA; its structure consisting of 11 CYS2-HIS2 ZINC FINGERS allows it to recognize many different DNA target sites. It functions as a repressor by binding to INSULATOR ELEMENTS and preventing interaction between promoters and nearby enhancers and silencers. It plays a critical role in EPIGENETIC PROCESSES, including GENOMIC IMPRINTING.

Descriptor ID	D000076246
MeSH Number(s)	D12.776.157.687.157 D12.776.260.120 D12.776.660.235.050 D12.776.660.720.157 D12.776.664.235.050 D12.776.930.780.563
Concept/Terms	CCCTC-Binding Factor CCCTC-Binding Factor CCCTC Binding Factor DNA-Binding Protein CTCF CTCF, DNA-Binding Protein DNA Binding Protein CTCF CTCF Protein

Below are MeSH descriptors whose meaning is more general than "CCCTC-Binding Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Poly-ADP-Ribose Binding Proteins [D12.776.157.687]
CCCTC-Binding Factor [D12.776.157.687.157]
DNA-Binding Proteins [D12.776.260]
CCCTC-Binding Factor [D12.776.260.120]
Nuclear Proteins [D12.776.660]
Chromosomal Proteins, Non-Histone [D12.776.660.235]
CCCTC-Binding Factor [D12.776.660.235.050]
Poly-ADP-Ribose Binding Proteins [D12.776.660.720]
CCCTC-Binding Factor [D12.776.660.720.157]
Nucleoproteins [D12.776.664]
Chromosomal Proteins, Non-Histone [D12.776.664.235]
CCCTC-Binding Factor [D12.776.664.235.050]
Transcription Factors [D12.776.930]
Repressor Proteins [D12.776.930.780]
CCCTC-Binding Factor [D12.776.930.780.563]

Below are MeSH descriptors whose meaning is related to "CCCTC-Binding Factor".

Below are MeSH descriptors whose meaning is more specific than "CCCTC-Binding Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CCCTC-Binding Factor" by people in this website by year, and whether "CCCTC-Binding Factor" was a major or minor topic of these publications.

Bar chart showing 4 publications over 3 distinct years, with a maximum of 2 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	0	1	1
2015	0	1	1
2018	1	1	2

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