"Orphan Nuclear Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad category of receptor-like proteins that may play a role in transcriptional-regulation in the CELL NUCLEUS. Many of these proteins are similar in structure to known NUCLEAR RECEPTORS but appear to lack a functional ligand-binding domain, while in other cases the specific ligands have yet to be identified.
| Descriptor ID |
D057093
|
| MeSH Number(s) |
D12.776.260.643 D12.776.826.209 D12.776.930.645
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Orphan Nuclear Receptors".
Below are MeSH descriptors whose meaning is more specific than "Orphan Nuclear Receptors".
- Orphan Nuclear Receptors
- COUP Transcription Factors
- Nuclear Receptor Subfamily 1, Group D, Member 1
- Nuclear Receptor Subfamily 1, Group F, Member 1
- Nuclear Receptor Subfamily 1, Group F, Member 2
- Nuclear Receptor Subfamily 1, Group F, Member 3
- Nuclear Receptor Subfamily 2, Group C, Member 1
- Nuclear Receptor Subfamily 2, Group C, Member 2
- Nuclear Receptor Subfamily 4, Group A, Member 1
- Nuclear Receptor Subfamily 4, Group A, Member 2
- Nuclear Receptor Subfamily 4, Group A, Member 3
- Nuclear Receptor Subfamily 6, Group A, Member 1
- Receptors, Aryl Hydrocarbon
This graph shows the total number of publications written about "Orphan Nuclear Receptors" by people in this website by year, and whether "Orphan Nuclear Receptors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Orphan Nuclear Receptors" by people in Profiles.
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Liver X receptor and peroxisome proliferator-activated receptor agonist from Cornus alternifolia. Biochim Biophys Acta. 2012 Jul; 1820(7):1021-6.
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Modulation of ABCA1 by an LXR agonist reduces ?-amyloid levels and improves outcome after traumatic brain injury. J Neurotrauma. 2011 Feb; 28(2):225-36.
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High-density lipoprotein metabolism and the human embryo. Hum Reprod Update. 2010 Jan-Feb; 16(1):20-38.
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Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009 Mar 15; 23(6):681-93.
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Differential expression of cholesterol hydroxylases in Alzheimer's disease. J Biol Chem. 2004 Aug 13; 279(33):34674-81.