CCAAT-Enhancer-Binding Proteins

"CCAAT-Enhancer-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of proteins that were originally identified by their ability to bind the DNA sequence CCAAT. The typical CCAAT-enhancer binding protein forms dimers and consists of an activation domain, a DNA-binding basic region, and a leucine-rich dimerization domain (LEUCINE ZIPPERS). CCAAT-BINDING FACTOR is structurally distinct type of CCAAT-enhancer binding protein consisting of a trimer of three different subunits.

Descriptor ID	D022762
MeSH Number(s)	D12.776.260.108.124 D12.776.660.167 D12.776.930.127.124
Concept/Terms	CCAAT-Enhancer-Binding Proteins CCAAT-Enhancer-Binding Proteins CCAAT Enhancer Binding Proteins CAAT-Enhancer Binding Protein Binding Protein, CAAT-Enhancer CAAT Enhancer Binding Protein CCAAT-Enhancer-Binding Protein CCAAT Enhancer Binding Protein C-EBP Protein C EBP Protein C-EBP Nuclear Protein C EBP Nuclear Protein Nuclear Protein, C-EBP CAAT-Enhancer-Binding Proteins CAAT Enhancer Binding Proteins C-EBP Proteins C EBP Proteins CCAAT Sequence-Specific DNA-Binding Proteins CCAAT Sequence Specific DNA Binding Proteins Nuclear Protein C-EBP C-EBP, Nuclear Protein Nuclear Protein C EBP

Below are MeSH descriptors whose meaning is more general than "CCAAT-Enhancer-Binding Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic-Leucine Zipper Transcription Factors [D12.776.260.108]
CCAAT-Enhancer-Binding Proteins [D12.776.260.108.124]
Nuclear Proteins [D12.776.660]
CCAAT-Enhancer-Binding Proteins [D12.776.660.167]
Transcription Factors [D12.776.930]
Basic-Leucine Zipper Transcription Factors [D12.776.930.127]
CCAAT-Enhancer-Binding Proteins [D12.776.930.127.124]

Below are MeSH descriptors whose meaning is related to "CCAAT-Enhancer-Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "CCAAT-Enhancer-Binding Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CCAAT-Enhancer-Binding Proteins" by people in this website by year, and whether "CCAAT-Enhancer-Binding Proteins" was a major or minor topic of these publications.

Bar chart showing 12 publications over 9 distinct years, with a maximum of 2 publications in 2000 and 2003 and 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
2000	0	2	2
2002	1	0	1
2003	1	1	2
2005	1	1	2
2012	0	1	1
2013	1	0	1
2016	0	1	1
2017	0	1	1

Below are the most recent publications written about "CCAAT-Enhancer-Binding Proteins" by people in Profiles.

Yiew NKH, Chatterjee TK, Tang YL, Pellenberg R, Stansfield BK, Bagi Z, Fulton DJ, Stepp DW, Chen W, Patel V, Kamath VM, Litwin SE, Hui DY, Rudich SM, Kim HW, Weintraub NL. A novel role for the Wnt inhibitor APCDD1 in adipocyte differentiation: Implications for diet-induced obesity. J Biol Chem. 2017 04 14; 292(15):6312-6324.

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Maharry SE, Walker CJ, Liyanarachchi S, Mehta S, Patel M, Bainazar MA, Huang X, Lankenau MA, Hoag KW, Ranganathan P, Garzon R, Blachly JS, Guttridge DC, Bloomfield CD, de la Chapelle A, Eisfeld AK. Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia. Cancer Discov. 2016 09; 6(9):1036-51.

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Hegde VL, Tomar S, Jackson A, Rao R, Yang X, Singh UP, Singh NP, Nagarkatti PS, Nagarkatti M. Distinct microRNA expression profile and targeted biological pathways in functional myeloid-derived suppressor cells induced by ?9-tetrahydrocannabinol in vivo: regulation of CCAAT/enhancer-binding protein a by microRNA-690. J Biol Chem. 2013 Dec 27; 288(52):36810-26.

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Sawant A, Chanda D, Isayeva T, Tsuladze G, Garvey WT, Ponnazhagan S. Noggin is novel inducer of mesenchymal stem cell adipogenesis: implications for bone health and obesity. J Biol Chem. 2012 Apr 06; 287(15):12241-9.

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Berquin IM, Pang B, Dziubinski ML, Scott LM, Chen YQ, Nolan GP, Ethier SP. Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells. Oncogene. 2005 Apr 28; 24(19):3177-86.

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Fu Y, Luo N, Klein RL, Garvey WT. Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation. J Lipid Res. 2005 Jul; 46(7):1369-79.

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Won JS, Im YB, Key L, Singh I, Singh AK. The involvement of glucose metabolism in the regulation of inducible nitric oxide synthase gene expression in glial cells: possible role of glucose-6-phosphate dehydrogenase and CCAAT/enhancing binding protein. J Neurosci. 2003 Aug 20; 23(20):7470-8.

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Fu Y, Huang Y, Bandyopadhyay S, Virella G, Lopes-Virella MF. LDL immune complexes stimulate LDL receptor expression in U937 histiocytes via extracellular signal-regulated kinase and AP-1. J Lipid Res. 2003 Jul; 44(7):1315-21.

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Giri S, Jatana M, Rattan R, Won JS, Singh I, Singh AK. Galactosylsphingosine (psychosine)-induced expression of cytokine-mediated inducible nitric oxide synthases via AP-1 and C/EBP: implications for Krabbe disease. FASEB J. 2002 May; 16(7):661-72.

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Slomiany BA, D'Arigo KL, Kelly MM, Kurtz DT. C/EBPalpha inhibits cell growth via direct repression of E2F-DP-mediated transcription. Mol Cell Biol. 2000 Aug; 20(16):5986-97.

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