Kruppel-Like Transcription Factors

"Kruppel-Like Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of zinc finger transcription factors that share homology with Kruppel protein, Drosophila. They contain a highly conserved seven amino acid spacer sequence in between their ZINC FINGER MOTIFS.

Descriptor ID	D051741
MeSH Number(s)	D12.776.260.522 D12.776.930.375
Concept/Terms	Kruppel-Like Transcription Factors Kruppel-Like Transcription Factors Kruppel Like Transcription Factors Transcription Factors, Kruppel-Like Kruppel-Like Factors Kruppel Like Factors

Below are MeSH descriptors whose meaning is more general than "Kruppel-Like Transcription Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Kruppel-Like Transcription Factors [D12.776.260.522]
Transcription Factors [D12.776.930]
Kruppel-Like Transcription Factors [D12.776.930.375]

Below are MeSH descriptors whose meaning is related to "Kruppel-Like Transcription Factors".

Below are MeSH descriptors whose meaning is more specific than "Kruppel-Like Transcription Factors".

Kruppel-Like Transcription Factors
Ikaros Transcription Factor
Kruppel-Like Factor 6
Promyelocytic Leukemia Zinc Finger Protein
Sp Transcription Factors
Zinc Finger Protein Gli3

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Kruppel-Like Transcription Factors" by people in this website by year, and whether "Kruppel-Like Transcription Factors" was a major or minor topic of these publications.

Bar chart showing 19 publications over 12 distinct years, with a maximum of 3 publications in 2014 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2005	0	1	1
2006	0	1	1
2009	1	1	2
2011	0	1	1
2012	1	0	1
2013	1	1	2
2014	0	3	3
2015	1	0	1
2016	2	1	3
2017	1	1	2
2019	0	1	1

Below are the most recent publications written about "Kruppel-Like Transcription Factors" by people in Profiles.

Mehrpouya-Bahrami P, Miranda K, Singh NP, Zumbrun EE, Nagarkatti M, Nagarkatti PS. Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity. J Biol Chem. 2019 05 10; 294(19):7669-7681.

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Farris SP, Riley BP, Williams RW, Mulligan MK, Miles MF, Lopez MF, Hitzemann R, Iancu OD, Colville A, Walter NAR, Darakjian P, Oberbeck DL, Daunais JB, Zheng CL, Searles RP, McWeeney SK, Grant KA, Mayfield RD. Cross-species molecular dissection across alcohol behavioral domains. Alcohol. 2018 11; 72:19-31.

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Nimpong JA, Gebregziabher W, Singh UP, Nagarkatti P, Nagarkatti M, Hodge J, Liu C, Fan D, Ai W. Deficiency of KLF4 compromises the lung function in an acute mouse model of allergic asthma. Biochem Biophys Res Commun. 2017 11 04; 493(1):598-603.

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Wu M, Ingram L, Tolosa EJ, Vera RE, Li Q, Kim S, Ma Y, Spyropoulos DD, Beharry Z, Huang J, Fernandez-Zapico ME, Cai H. Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis. J Biol Chem. 2016 Dec 02; 291(49):25749-25760.

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Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, Fernandez SA, Rosol TJ, Lesinski GB, Shakya R, Ludwig T, Konieczny SF, Leone G, Wu J, Ostrowski MC. Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. Genes Dev. 2016 09 01; 30(17):1943-55.

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Kim SH, Park YY, Cho SN, Margalit O, Wang D, DuBois RN. Krüppel-Like Factor 12 Promotes Colorectal Cancer Growth through Early Growth Response Protein 1. PLoS One. 2016; 11(7):e0159899.

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Ou L, Shi Y, Dong W, Liu C, Schmidt TJ, Nagarkatti P, Nagarkatti M, Fan D, Ai W. Kruppel-like factor KLF4 facilitates cutaneous wound healing by promoting fibrocyte generation from myeloid-derived suppressor cells. J Invest Dermatol. 2015 May; 135(5):1425-1434.

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Weber CE, Kothari AN, Wai PY, Li NY, Driver J, Zapf MA, Franzen CA, Gupta GN, Osipo C, Zlobin A, Syn WK, Zhang J, Kuo PC, Mi Z. Osteopontin mediates an MZF1-TGF-ß1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer. Oncogene. 2015 Sep 10; 34(37):4821-33.

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Liu JT, Bain LJ. Arsenic inhibits hedgehog signaling during P19 cell differentiation. Toxicol Appl Pharmacol. 2014 Dec 15; 281(3):243-53.

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Long J, Li B, Rodriguez-Blanco J, Pastori C, Volmar CH, Wahlestedt C, Capobianco A, Bai F, Pei XH, Ayad NG, Robbins DJ. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers. J Biol Chem. 2014 Dec 19; 289(51):35494-502.

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