Syk Kinase

"Syk Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.

Descriptor ID	D000072377
MeSH Number(s)	D08.811.913.696.620.682.725.650 D12.644.360.900 D12.776.476.913
Concept/Terms	Syk Kinase Syk Kinase Kinase, Syk SYK Tyrosine Kinase Kinase, SYK Tyrosine Tyrosine Kinase, SYK Spleen Tyrosine Kinase Kinase, Spleen Tyrosine Tyrosine Kinase, Spleen

Below are MeSH descriptors whose meaning is more general than "Syk Kinase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Syk Kinase [D08.811.913.696.620.682.725.650]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Syk Kinase [D12.644.360.900]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Syk Kinase [D12.776.476.913]

Below are MeSH descriptors whose meaning is related to "Syk Kinase".

Below are MeSH descriptors whose meaning is more specific than "Syk Kinase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Syk Kinase" by people in this website by year, and whether "Syk Kinase" was a major or minor topic of these publications.

Bar chart showing 9 publications over 6 distinct years, with a maximum of 2 publications in 1999 and 2002 and 2019

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1996	1	1
1999	2	2
2002	2	2
2006	1	1
2010	1	1
2019	2	2

Below are the most recent publications written about "Syk Kinase" by people in Profiles.

Kaplan AP. Basophil histamine release in patients with chronic spontaneous urticaria: Optimize or minimize. J Allergy Clin Immunol. 2019 08; 144(2):622-623.

View in: PubMed
Abebayehu D, Spence AJ, Caslin H, Taruselli M, Haque TT, Kiwanuka KN, Kolawole EM, Chumanevich AP, Sell SA, Oskeritzian CA, Ryan J, Kee SA. Lactic acid suppresses IgE-mediated mast cell function in vitro and in vivo. Cell Immunol. 2019 07; 341:103918.

View in: PubMed
Shanmugarajan S, Beeson CC, Reddy SV. Osteoclast inhibitory peptide-1 binding to the Fc gammaRIIB inhibits osteoclast differentiation. Endocrinology. 2010 Sep; 151(9):4389-99.

View in: PubMed
Hirahashi J, Mekala D, Van Ziffle J, Xiao L, Saffaripour S, Wagner DD, Shapiro SD, Lowell C, Mayadas TN. Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy. Immunity. 2006 Aug; 25(2):271-83.

View in: PubMed
Kabak S, Skaggs BJ, Gold MR, Affolter M, West KL, Foster MS, Siemasko K, Chan AC, Aebersold R, Clark MR. The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways. Mol Cell Biol. 2002 Apr; 22(8):2524-35.

View in: PubMed
Mustelin T, Abraham RT, Rudd CE, Alonso A, Merlo JJ. Protein tyrosine phosphorylation in T cell signaling. Front Biosci. 2002 Apr 01; 7:d918-69.

View in: PubMed
Feuerstein N, Chen F, Madaio M, Maldonado M, Eisenberg RA. Induction of autoimmunity in a transgenic model of B cell receptor peripheral tolerance: changes in coreceptors and B cell receptor-induced tyrosine-phosphoproteins. J Immunol. 1999 Nov 15; 163(10):5287-97.

View in: PubMed
Gold MR, Scheid MP, Santos L, Dang-Lawson M, Roth RA, Matsuuchi L, Duronio V, Krebs DL. The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase. J Immunol. 1999 Aug 15; 163(4):1894-905.

View in: PubMed
Richards JD, Gold MR, Hourihane SL, DeFranco AL, Matsuuchi L. Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase. J Biol Chem. 1996 Mar 15; 271(11):6458-66.

View in: PubMed

People

Explore

Similar Concepts

Top Journals