| Item Type | Name |
|
Academic Article
|
Energy deprivation and a deficiency in downstream metabolic target genes during the onset of embryonic heart failure in RXRalpha-/- embryos.
|
|
Academic Article
|
The molecular genetics of retinoic acid receptors: cardiovascular and limb development.
|
|
Concept
|
Teratogens
|
|
Concept
|
Microscopy, Electron, Scanning
|
|
Concept
|
Cytokines
|
|
Concept
|
Muscle, Smooth, Vascular
|
|
Concept
|
Oligodeoxyribonucleotides, Antisense
|
|
Concept
|
Membrane Proteins
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Basic Helix-Loop-Helix Transcription Factors
|
|
Concept
|
Protein Binding
|
|
Concept
|
Genes, Lethal
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Hepatocyte Nuclear Factor 4
|
|
Concept
|
Mandible
|
|
Concept
|
Early Growth Response Protein 2
|
|
Concept
|
DNA-Binding Proteins
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
Sea Urchins
|
|
Concept
|
Salivary Glands
|
|
Concept
|
Bone Development
|
|
Concept
|
Integrases
|
|
Concept
|
Cell Lineage
|
|
Concept
|
Animals, Newborn
|
|
Concept
|
Neuregulins
|
|
Concept
|
Fibroblast Growth Factor 8
|
|
Concept
|
Erythroid Precursor Cells
|
|
Concept
|
DiGeorge Syndrome
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Microscopy, Video
|
|
Concept
|
Endocardial Cushions
|
|
Concept
|
Odontogenesis
|
|
Concept
|
Endocardium
|
|
Concept
|
Tumor Suppressor Protein p53
|
|
Concept
|
Prostatic Neoplasms
|
|
Concept
|
Excitatory Postsynaptic Potentials
|
|
Concept
|
Erythropoietin
|
|
Concept
|
Insulin Receptor Substrate Proteins
|
|
Concept
|
Embryo, Mammalian
|
|
Concept
|
Cell Nucleus
|
|
Concept
|
Retinoid X Receptor alpha
|
|
Concept
|
Cell Division
|
|
Concept
|
Wnt1 Protein
|
|
Concept
|
Tooth
|
|
Concept
|
Fatty Acid-Binding Proteins
|
|
Concept
|
Actins
|
|
Concept
|
Gene Expression
|
|
Concept
|
Peroxisome Proliferators
|
|
Concept
|
Receptors, Transforming Growth Factor beta
|
|
Concept
|
Myosins
|
|
Concept
|
Receptors, Endothelin
|
|
Concept
|
Receptor, Platelet-Derived Growth Factor alpha
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Long-Term Potentiation
|
|
Concept
|
Cadherins
|
|
Concept
|
Organogenesis
|
|
Concept
|
Receptor, IGF Type 1
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
Axons
|
|
Concept
|
Aorta, Thoracic
|
|
Concept
|
Cues
|
|
Concept
|
Neurites
|
|
Concept
|
Neuropilins
|
|
Concept
|
Electron Transport Complex I
|
|
Concept
|
Tretinoin
|
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p19
|
|
Concept
|
Coronary Vessel Anomalies
|
|
Concept
|
NIH 3T3 Cells
|
|
Concept
|
Receptor, IGF Type 2
|
|
Concept
|
Animals
|
|
Concept
|
Binding, Competitive
|
|
Concept
|
Carrier Proteins
|
|
Concept
|
Mammals
|
|
Concept
|
Genes
|
|
Concept
|
Receptors, Erythropoietin
|
|
Concept
|
Osteogenesis
|
|
Concept
|
Platelet-Derived Growth Factor
|
|
Concept
|
Cell Cycle Proteins
|
|
Concept
|
Trans-Activators
|
|
Concept
|
Synaptic Transmission
|
|
Concept
|
Adenosine Triphosphate
|
|
Concept
|
Protein Biosynthesis
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Heart Valves
|
|
Concept
|
Receptors, Atrial Natriuretic Factor
|
|
Concept
|
Deoxyribonuclease EcoRI
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Superior Cervical Ganglion
|
|
Concept
|
Fibrin
|
|
Concept
|
Lac Operon
|
|
Concept
|
Cytochrome P-450 Enzyme System
|
|
Concept
|
Myocytes, Cardiac
|
|
Concept
|
Nuclear Proteins
|
|
Concept
|
Mitogens
|
|
Concept
|
Coronary Vessels
|
|
Concept
|
Pulmonary Artery
|
|
Concept
|
Transforming Growth Factor beta2
|
|
Concept
|
Twist-Related Protein 1
|
|
Concept
|
Protein Kinases
|
|
Concept
|
T-Lymphocytes, Regulatory
|
|
Concept
|
Myosin Light Chains
|
|
Concept
|
Arteries
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Heart Failure
|
|
Concept
|
Parietal Bone
|
|
Concept
|
Heart Defects, Congenital
|
|
Concept
|
Retinoids
|
|
Concept
|
Chloramphenicol O-Acetyltransferase
|
|
Concept
|
Hyaluronan Receptors
|
|
Concept
|
Myocardium
|
|
Concept
|
Receptors, Nerve Growth Factor
|
|
Concept
|
Extracellular Matrix Proteins
|
|
Concept
|
Acyl-CoA Oxidase
|
|
Concept
|
Energy Metabolism
|
|
Concept
|
Phenylephrine
|
|
Concept
|
Connexin 43
|
|
Concept
|
MSX1 Transcription Factor
|
|
Concept
|
Mice
|
|
Concept
|
Mesoderm
|
|
Concept
|
Keratolytic Agents
|
|
Concept
|
Cell Line, Transformed
|
|
Concept
|
Frontal Bone
|
|
Concept
|
DNA Primers
|
|
Concept
|
Umbilical Veins
|
|
Concept
|
Models, Biological
|
|
Concept
|
Vitamin A
|
|
Concept
|
Fetal Heart
|
|
Concept
|
Hypoxia-Inducible Factor 1
|
|
Concept
|
Dental Enamel
|
|
Concept
|
Germ-Line Mutation
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
Microscopy, Confocal
|
|
Concept
|
Dimerization
|
|
Concept
|
Viral Proteins
|
|
Concept
|
Mice, Inbred ICR
|
|
Concept
|
Repressor Proteins
|
|
Concept
|
Neuronal Plasticity
|
|
Concept
|
Matrix Metalloproteinase 9
|
|
Concept
|
Exons
|
|
Concept
|
Growth Substances
|
|
Concept
|
Protein-Arginine N-Methyltransferases
|
|
Concept
|
Embryonic and Fetal Development
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
Mosaicism
|
|
Concept
|
Bone Morphogenetic Proteins
|
|
Concept
|
Maze Learning
|
|
Concept
|
Endoderm
|
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p16
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
Transcription Factor AP-2
|
|
Concept
|
Cell Hypoxia
|
|
Concept
|
Rhombencephalon
|
|
Concept
|
Veins
|
|
Concept
|
Activated-Leukocyte Cell Adhesion Molecule
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Mitochondria, Heart
|
|
Concept
|
Proteins
|
|
Concept
|
Animals, Genetically Modified
|
|
Concept
|
Zebrafish Proteins
|
|
Concept
|
Oxygen
|
|
Concept
|
Organ Culture Techniques
|
|
Concept
|
Antigens, CD
|
|
Concept
|
Receptor, Insulin
|
|
Concept
|
Mole Rats
|
|
Concept
|
Erythroid-Specific DNA-Binding Factors
|
|
Concept
|
Somatomedins
|
|
Concept
|
Drosophila
|
|
Concept
|
Limb Deformities, Congenital
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Paired Box Transcription Factors
|
|
Concept
|
Hormones
|
|
Concept
|
Humans
|
|
Concept
|
Esophagus
|
|
Concept
|
Receptor, EphA4
|
|
Concept
|
Heart
|
|
Concept
|
Pericardium
|
|
Concept
|
Deoxyribonuclease BamHI
|
|
Concept
|
Transgenes
|
|
Concept
|
Prostate
|
|
Concept
|
Cell Movement
|
|
Concept
|
Heart Conduction System
|
|
Concept
|
Homeodomain Proteins
|
|
Concept
|
beta Catenin
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Apolipoprotein A-I
|
|
Concept
|
Retinoid X Receptors
|
|
Concept
|
Neural Tube Defects
|
|
Concept
|
Cytochrome P-450 CYP4A
|
|
Concept
|
Cytoskeletal Proteins
|
|
Concept
|
Endocardial Cushion Defects
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Cardiomegaly
|
|
Concept
|
Receptor, Notch1
|
|
Concept
|
Lymphocytes
|
|
Concept
|
Thrombospondins
|
|
Concept
|
Receptors, CXCR4
|
|
Concept
|
Heart Atria
|
|
Concept
|
Epithelium
|
|
Concept
|
Cranial Sutures
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Receptors, Adrenergic, alpha
|
|
Concept
|
Synapses
|
|
Concept
|
Insulin-Like Growth Factor Binding Protein 2
|
|
Concept
|
Apolipoproteins C
|
|
Concept
|
Protein Multimerization
|
|
Concept
|
Aorta
|
|
Concept
|
Gestational Age
|
|
Concept
|
Apolipoprotein C-III
|
|
Concept
|
Antigens, Surface
|
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
|
Concept
|
Smad3 Protein
|
|
Concept
|
Gene Knock-In Techniques
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Thymus Gland
|
|
Concept
|
Truncus Arteriosus, Persistent
|
|
Concept
|
Recombinant Fusion Proteins
|
|
Concept
|
Cell Culture Techniques
|
|
Concept
|
Lymphocyte Activation
|
|
Concept
|
Calcium-Binding Proteins
|
|
Concept
|
Smad4 Protein
|
|
Concept
|
Insulin-Like Growth Factor II
|
|
Concept
|
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
|
|
Concept
|
DNA Probes
|
|
Concept
|
Chemokines, CXC
|
|
Concept
|
Neoplasm Proteins
|
|
Concept
|
Mice, Inbred Strains
|
|
Concept
|
Desmin
|
|
Concept
|
Protein-Lysine 6-Oxidase
|
|
Concept
|
Ovary
|
|
Concept
|
Receptor, TIE-2
|
|
Concept
|
Wnt Proteins
|
|
Concept
|
Rats
|
|
Concept
|
Activin Receptors, Type I
|
|
Concept
|
Skull
|
|
Concept
|
Calcitonin
|
|
Concept
|
PPAR gamma
|
|
Concept
|
Spleen
|
|
Concept
|
Carotid Arteries
|
|
Concept
|
Rats, Mutant Strains
|
|
Concept
|
Sequence Homology, Nucleic Acid
|
|
Concept
|
In Situ Hybridization
|
|
Concept
|
Trophoblasts
|
|
Concept
|
Angiopoietin-1
|
|
Concept
|
Materials Testing
|
|
Concept
|
Amelogenin
|
|
Concept
|
Tamoxifen
|
|
Concept
|
Endothelin-3
|
|
Concept
|
Cell Line
|
|
Concept
|
DNA Restriction Enzymes
|
|
Concept
|
Heart Ventricles
|
|
Concept
|
Chimera
|
|
Concept
|
Body Patterning
|
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p27
|
|
Concept
|
Angiography
|
|
Concept
|
Receptors, Notch
|
|
Concept
|
Polymerase Chain Reaction
|
|
Concept
|
Myelin P2 Protein
|
|
Concept
|
Cardiovascular Abnormalities
|
|
Concept
|
Hippocampus
|
|
Concept
|
Protein Isoforms
|
|
Concept
|
Culture Media, Conditioned
|
|
Concept
|
Polyploidy
|
|
Concept
|
Retinal Dehydrogenase
|
|
Concept
|
Myocardial Contraction
|
|
Concept
|
Guanine Nucleotide Dissociation Inhibitors
|
|
Concept
|
Nervous System Malformations
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Cholesterol
|
|
Concept
|
Mice, Inbred DBA
|
|
Concept
|
In Situ Hybridization, Fluorescence
|
|
Concept
|
Cardiomyopathy, Dilated
|
|
Concept
|
Testis
|
|
Concept
|
Hepatic Stellate Cells
|
|
Concept
|
Bone Morphogenetic Protein 2
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
Bone Morphogenetic Protein 4
|
|
Concept
|
Proto-Oncogene Proteins
|
|
Concept
|
Gene Silencing
|
|
Concept
|
Base Sequence
|
|
Concept
|
Alleles
|
|
Concept
|
RNA Probes
|
|
Concept
|
Zebrafish
|
|
Concept
|
Genes, Homeobox
|
|
Concept
|
Heart Septal Defects
|
|
Concept
|
Endothelium
|
|
Concept
|
Embryonic Development
|
|
Concept
|
Heart Diseases
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Cleft Palate
|
|
Concept
|
Nerve Tissue Proteins
|
|
Concept
|
Mice, Mutant Strains
|
|
Concept
|
Endothelins
|
|
Concept
|
Molecular Sequence Data
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Immunoblotting
|
|
Concept
|
Chemokine CXCL12
|
|
Concept
|
Space Perception
|
|
Concept
|
Atrial Natriuretic Factor
|
|
Concept
|
Heart Septal Defects, Ventricular
|
|
Academic Article
|
Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation.
|
|
Academic Article
|
Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene.
|
|
Academic Article
|
A lineage-specific gene encoding a major matrix protein of the sea urchin embryo spicule. II. Structure of the gene and derived sequence of the protein.
|
|
Academic Article
|
A regulatory domain that directs lineage-specific expression of a skeletal matrix protein gene in the sea urchin embryo.
|
|
Academic Article
|
A lineage-specific gene encoding a major matrix protein of the sea urchin embryo spicule. I. Authentication of the cloned gene and its developmental expression.
|
|
Academic Article
|
Lineage-specific gene expression in the sea urchin embryo.
|
|
Academic Article
|
Retinoic acid and retinoic acid receptors in development.
|
|
Academic Article
|
Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene.
|
|
Academic Article
|
Mouse embryos lacking RXR alpha are resistant to retinoic-acid-induced limb defects.
|
|
Academic Article
|
Genetic analysis of the retinoid signal.
|
|
Academic Article
|
Compound mutants for retinoic acid receptor (RAR) beta and RAR alpha 1 reveal developmental functions for multiple RAR beta isoforms.
|
|
Academic Article
|
Molecular insights into cardiac development.
|
|
Academic Article
|
An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression.
|
|
Academic Article
|
The role of RXR-alpha in retinoic acid-induced cleft palate as assessed with the RXR-alpha knockout mouse.
|
|
Academic Article
|
Fate of the mammalian cardiac neural crest.
|
|
Academic Article
|
Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis.
|
|
Academic Article
|
Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver.
|
|
Academic Article
|
Peroxisome proliferator-activated receptor alpha-mediated pathways are altered in hepatocyte-specific retinoid X receptor alpha-deficient mice.
|
|
Academic Article
|
Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation.
|
|
Academic Article
|
A developmental transition in definitive erythropoiesis: erythropoietin expression is sequentially regulated by retinoic acid receptors and HNF4.
|
|
Academic Article
|
Requirement for AP-2alpha in cardiac outflow tract morphogenesis.
|
|
Academic Article
|
Tissue origins and interactions in the mammalian skull vault.
|
|
Academic Article
|
Msx2 is an immediate downstream effector of Pax3 in the development of the murine cardiac neural crest.
|
|
Academic Article
|
Cranial neural crest-derived mesenchymal proliferation is regulated by Msx1-mediated p19(INK4d) expression during odontogenesis.
|
|
Academic Article
|
Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault.
|
|
Academic Article
|
The role of erythropoietin in regulating angiogenesis.
|
|
Academic Article
|
Convergent proliferative response and divergent morphogenic pathways induced by epicardial and endocardial signaling in fetal heart development.
|
|
Academic Article
|
Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest.
|
|
Academic Article
|
Cardiovascular malformations with normal smooth muscle differentiation in neural crest-specific type II TGFbeta receptor (Tgfbr2) mutant mice.
|
|
Academic Article
|
Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects.
|
|
Academic Article
|
Expression of the epithelial marker E-cadherin by thyroid C cells and their precursors during murine development.
|
|
Academic Article
|
Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract.
|
|
Academic Article
|
PDGF-A as an epicardial mitogen during heart development.
|
|
Academic Article
|
Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons.
|
|
Academic Article
|
Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium.
|
|
Academic Article
|
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.
|
|
Academic Article
|
Absence of TGFbeta signaling in embryonic vascular smooth muscle leads to reduced lysyl oxidase expression, impaired elastogenesis, and aneurysm.
|
|
Academic Article
|
Epicardial control of myocardial proliferation and morphogenesis.
|
|
Academic Article
|
Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines.
|
|
Academic Article
|
Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation.
|
|
Academic Article
|
Retinoic acid stimulates myocardial expansion by induction of hepatic erythropoietin which activates epicardial Igf2.
|
|
Academic Article
|
A simplified genetic design for mammalian enamel.
|
|
Academic Article
|
IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.
|
|
Academic Article
|
Mesodermal retinoic acid signaling regulates endothelial cell coalescence in caudal pharyngeal arch artery vasculogenesis.
|
|
Academic Article
|
Endothelial neuropilin disruption in mice causes DiGeorge syndrome-like malformations via mechanisms distinct to those caused by loss of Tbx1.
|
|
Academic Article
|
Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration.
|
|
Academic Article
|
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons.
|
|
Academic Article
|
Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3.
|
|
Academic Article
|
Extracardiac control of embryonic cardiomyocyte proliferation and ventricular wall expansion.
|
|
Academic Article
|
Adipogenesis and epicardial adipose tissue: a novel fate of the epicardium induced by mesenchymal transformation and PPAR? activation.
|
|
Academic Article
|
Chemokine-guided angiogenesis directs coronary vasculature formation in zebrafish.
|
|
Academic Article
|
CXCL12 Signaling Is Essential for Maturation of the Ventricular Coronary Endothelial Plexus and Establishment of Functional Coronary Circulation.
|
|
Academic Article
|
Dysregulated endocardial TGF? signaling and mesenchymal transformation result in heart outflow tract septation failure.
|
|
Academic Article
|
Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls.
|
|
Academic Article
|
Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration.
|
|
Academic Article
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Differential roles of insulin like growth factor 1 receptor and insulin receptor during embryonic heart development.
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Academic Article
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Phases and Mechanisms of Embryonic Cardiomyocyte Proliferation and Ventricular Wall Morphogenesis.
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Academic Article
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Cardiomyocyte Polyploidy and Implications for Heart Regeneration.
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Academic Article
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Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency.
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Academic Article
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Correction to: Phases and Mechanisms of Embryonic Cardiomyocyte Proliferation and Ventricular Wall Morphogenesis.
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Academic Article
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Apical Resection and Cryoinjury of Neonatal Mouse Heart.
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Academic Article
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The prevalent I686T human variant and loss-of-function mutations in the cardiomyocyte-specific kinase gene TNNI3K cause adverse contractility and concentric remodeling in mice.
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Academic Article
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Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy.
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Academic Article
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PRMT1-p53 Pathway Controls Epicardial EMT and Invasion.
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Academic Article
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Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling.
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Academic Article
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Delta-like ligand 4-mediated Notch signaling controls proliferation of second heart field progenitor cells by regulating Fgf8 expression.
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Concept
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Vascular Remodeling
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Concept
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Loss of Function Mutation
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Concept
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Fatty Acid-Binding Protein 7
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Concept
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PAX3 Transcription Factor
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Concept
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Retinoic Acid Receptor alpha
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Concept
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Retinoic Acid 4-Hydroxylase
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Concept
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Homeobox Protein Nkx-2.5
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Academic Article
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Measuring cardiomyocyte cell-cycle activity and proliferation in the age of heart regeneration.
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Academic Article
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Delta-like ligand-4 regulates Notch-mediated maturation of second heart field progenitor-derived pharyngeal arterial endothelial cells.
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Academic Article
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CITED2 is a conserved regulator of the uterine-placental interface.
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Academic Article
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Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury.
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Academic Article
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Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease.
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