Oncogene Protein v-akt

"Oncogene Protein v-akt" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A viral oncoprotein originally isolated from a murine T CELL LYMPHOMA infected with the acutely transforming retrovirus AKT8. v-akt protein is the viral homologue of PROTO-ONCOGENE PROTEINS C-AKT.

Descriptor ID	D051058
MeSH Number(s)	D08.811.913.696.620.682.700.586 D12.776.624.664.520.750.788
Concept/Terms	Oncogene Protein v-akt Oncogene Protein v-akt Oncogene Protein v akt v-akt, Oncogene Protein v-akt Protein v-akt Kinase Transforming Protein v akt Kinase Transforming Protein akt-Oncogene Protein akt Oncogene Protein Oncogene Protein akt akt, Oncogene Protein

Below are MeSH descriptors whose meaning is more general than "Oncogene Protein v-akt".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
Oncogene Protein v-akt [D08.811.913.696.620.682.700.586]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Oncogene Proteins, Viral [D12.776.624.664.520]
Retroviridae Proteins, Oncogenic [D12.776.624.664.520.750]
Oncogene Protein v-akt [D12.776.624.664.520.750.788]

Below are MeSH descriptors whose meaning is related to "Oncogene Protein v-akt".

Below are MeSH descriptors whose meaning is more specific than "Oncogene Protein v-akt".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Oncogene Protein v-akt" by people in this website by year, and whether "Oncogene Protein v-akt" was a major or minor topic of these publications.

Bar chart showing 15 publications over 12 distinct years, with a maximum of 2 publications in 2006 and 2007 and 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2005	1	0	1
2006	0	2	2
2007	1	1	2
2008	1	0	1
2010	0	1	1
2011	1	0	1
2012	0	2	2
2013	0	1	1
2014	0	1	1
2015	0	1	1
2019	0	1	1

Below are the most recent publications written about "Oncogene Protein v-akt" by people in Profiles.

Sun B, Mason S, Wilson RC, Hazard SE, Wang Y, Fang R, Wang Q, Yeh ES, Yang M, Roberts TM, Zhao JJ, Wang Q. Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers. Oncogene. 2020 01; 39(1):50-63.

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Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecót T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, Srivastava A, Yu L, Wallace J, Mo X, Park M, Fernandez SA, Pilarski R, La Perle KM, Rosol TJ, Coppola V, Castrillon DH, Timmers C, Cohn DE, O'Malley DM, Backes F, Suarez AA, Goodfellow P, Chamberlin HM, Macrae ER, Shapiro CL, Ostrowski MC, Leone G. Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo. Genes Dev. 2015 Aug 15; 29(16):1707-20.

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Subathra M, Korrapati M, Howell LA, Arthur JM, Shayman JA, Schnellmann RG, Siskind LJ. Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells. Am J Physiol Renal Physiol. 2015 Aug 01; 309(3):F204-15.

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Liu P, Begley M, Michowski W, Inuzuka H, Ginzberg M, Gao D, Tsou P, Gan W, Papa A, Kim BM, Wan L, Singh A, Zhai B, Yuan M, Wang Z, Gygi SP, Lee TH, Lu KP, Toker A, Pandolfi PP, Asara JM, Kirschner MW, Sicinski P, Cantley L, Wei W. Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus. Nature. 2014 Apr 24; 508(7497):541-5.

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Sundin T, Peffley D, Hentosh P. eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase. Exp Cell Res. 2013 Aug 01; 319(13):2103-2112.

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Smith AM, Findlay VJ, Bandurraga SG, Kistner-Griffin E, Spruill LS, Liu A, Golshayan AR, Turner DP. ETS1 transcriptional activity is increased in advanced prostate cancer and promotes the castrate-resistant phenotype. Carcinogenesis. 2012 Mar; 33(3):572-80.

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Sakakima H, Khan M, Dhammu TS, Shunmugavel A, Yoshida Y, Singh I, Singh AK. Stimulation of functional recovery via the mechanisms of neurorepair by S-nitrosoglutathione and motor exercise in a rat model of transient cerebral ischemia and reperfusion. Restor Neurol Neurosci. 2012; 30(5):383-96.

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Thomas B, Mandir AS, West N, Liu Y, Andrabi SA, Stirling W, Dawson VL, Dawson TM, Lee MK. Resistance to MPTP-neurotoxicity in a-synuclein knockout mice is complemented by human a-synuclein and associated with increased ß-synuclein and Akt activation. PLoS One. 2011 Jan 31; 6(1):e16706.

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Shi X, McGinty JF. D1 and D2 dopamine receptors differentially mediate the activation of phosphoproteins in the striatum of amphetamine-sensitized rats. Psychopharmacology (Berl). 2011 Apr; 214(3):653-63.

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Bujor AM, Pannu J, Bu S, Smith EA, Muise-Helmericks RC, Trojanowska M. Akt blockade downregulates collagen and upregulates MMP1 in human dermal fibroblasts. J Invest Dermatol. 2008 Aug; 128(8):1906-14.

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