AMP-Activated Protein Kinases

"AMP-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP.

Descriptor ID	D055372
MeSH Number(s)	D08.811.913.696.620.682.700.085 D12.644.360.062 D12.776.476.062
Concept/Terms	AMP-Activated Protein Kinases AMP-Activated Protein Kinases AMP Activated Protein Kinases AMP-Activated Kinase AMP Activated Kinase AMP-Activated Protein Kinase AMP Activated Protein Kinase 5'-AMP-Activated Protein Kinase 5' AMP Activated Protein Kinase AMP-Activated Protein Kinase beta Subunits AMP-Activated Protein Kinase beta Subunits AMP Activated Protein Kinase beta Subunits AMP-Activated Protein Kinase beta Subunit AMP Activated Protein Kinase beta Subunit AMP-Activated Protein Kinase gamma Subunits AMP-Activated Protein Kinase gamma Subunits AMP Activated Protein Kinase gamma Subunits AMP-Activated Protein Kinase gamma Subunit AMP Activated Protein Kinase gamma Subunit AMP-Activated Protein Kinase alpha Subunits AMP-Activated Protein Kinase alpha Subunits AMP Activated Protein Kinase alpha Subunits PRKAA AMP-Activated Protein Kinase alpha Subunit AMP Activated Protein Kinase alpha Subunit

Below are MeSH descriptors whose meaning is more general than "AMP-Activated Protein Kinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
AMP-Activated Protein Kinases [D08.811.913.696.620.682.700.085]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
AMP-Activated Protein Kinases [D12.644.360.062]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
AMP-Activated Protein Kinases [D12.776.476.062]

Below are MeSH descriptors whose meaning is related to "AMP-Activated Protein Kinases".

Below are MeSH descriptors whose meaning is more specific than "AMP-Activated Protein Kinases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "AMP-Activated Protein Kinases" by people in this website by year, and whether "AMP-Activated Protein Kinases" was a major or minor topic of these publications.

Bar chart showing 29 publications over 14 distinct years, with a maximum of 6 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	0	1	1
2005	0	2	2
2006	0	1	1
2007	0	2	2
2008	0	3	3
2009	3	1	4
2010	4	2	6
2013	1	0	1
2014	0	1	1
2015	0	1	1
2016	1	0	1
2017	0	1	1
2018	1	3	4
2022	0	1	1

Below are the most recent publications written about "AMP-Activated Protein Kinases" by people in Profiles.

Wu F, Hill K, Fang Q, He Z, Zheng H, Wang X, Xiong H, Sha SH. Traumatic-noise-induced hair cell death and hearing loss is mediated by activation of CaMKKß. Cell Mol Life Sci. 2022 Apr 19; 79(5):249.

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Yu J, Zhu H, Taheri S, Perry S, Kindy MS. The Effect of Diet on Improved Endurance in Male C57BL/6 Mice. Nutrients. 2018 Aug 16; 10(8).

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Khan M, Shunmugavel A, Dhammu TS, Khan H, Singh I, Singh AK. Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI. J Neurosci Res. 2018 12; 96(12):1900-1913.

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Singh I, Samuvel DJ, Choi S, Saxena N, Singh AK, Won J. Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model. Immunology. 2018 07; 154(3):434-451.

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Xie X, Hu H, Tong X, Li L, Liu X, Chen M, Yuan H, Xie X, Li Q, Zhang Y, Ouyang H, Wei M, Huang J, Liu P, Gan W, Liu Y, Xie A, Kuai X, Chirn GW, Zhou H, Zeng R, Hu R, Qin J, Meng FL, Wei W, Ji H, Gao D. The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168. Nat Cell Biol. 2018 03; 20(3):320-331.

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Ollila S, Domènech-Moreno E, Laajanen K, Wong IP, Tripathi S, Pentinmikko N, Gao Y, Yan Y, Niemelä EH, Wang TC, Viollet B, Leone G, Katajisto P, Vaahtomeri K, Mäkelä TP. Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. J Clin Invest. 2018 01 02; 128(1):402-414.

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Hill K, Yuan H, Wang X, Sha SH. Noise-Induced Loss of Hair Cells and Cochlear Synaptopathy Are Mediated by the Activation of AMPK. J Neurosci. 2016 07 13; 36(28):7497-510.

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Bikas A, Jensen K, Patel A, Costello J, McDaniel D, Klubo-Gwiezdzinska J, Larin O, Hoperia V, Burman KD, Boyle L, Wartofsky L, Vasko V. Glucose-deprivation increases thyroid cancer cells sensitivity to metformin. Endocr Relat Cancer. 2015 Dec; 22(6):919-32.

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Zheng HW, Chen J, Sha SH. Receptor-interacting protein kinases modulate noise-induced sensory hair cell death. Cell Death Dis. 2014 May 29; 5:e1262.

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Paintlia AS, Paintlia MK, Mohan S, Singh AK, Singh I. AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model. Am J Pathol. 2013 Aug; 183(2):526-41.

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