Tristetraprolin

"Tristetraprolin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A ZINC FINGER MOTIF containing transcription factor that was originally identified as one of the IMMEDIATE-EARLY PROTEINS. It shuttles between the CYTOPLASM and the CELL NUCLEUS and is involved in destabilization of mRNAs for TUMOR NECROSIS FACTOR-ALPHA.

Descriptor ID	D051816
MeSH Number(s)	D12.776.260.790 D12.776.460.762 D12.776.930.960
Concept/Terms	Tristetraprolin Tristetraprolin Tristetraprolin Protein G0-G1 Switch Regulatory Protein 24 G0 G1 Switch Regulatory Protein 24 Zinc Finger Protein 36

Below are MeSH descriptors whose meaning is more general than "Tristetraprolin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Tristetraprolin [D12.776.260.790]
Immediate-Early Proteins [D12.776.460]
Tristetraprolin [D12.776.460.762]
Transcription Factors [D12.776.930]
Tristetraprolin [D12.776.930.960]

Below are MeSH descriptors whose meaning is related to "Tristetraprolin".

Below are MeSH descriptors whose meaning is more specific than "Tristetraprolin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tristetraprolin" by people in this website by year, and whether "Tristetraprolin" was a major or minor topic of these publications.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 1996 and 1997 and 2009 and 2011 and 2018 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	0	1	1
2009	1	0	1
2011	0	1	1
2018	1	0	1
2020	1	0	1

Below are the most recent publications written about "Tristetraprolin" by people in Profiles.

Saaoud F, Wang J, Iwanowycz S, Wang Y, Altomare D, Shao Y, Liu J, Blackshear PJ, Lessner SM, Murphy EA, Wang H, Yang X, Fan D. Bone marrow deficiency of mRNA decaying protein Tristetraprolin increases inflammation and mitochondrial ROS but reduces hepatic lipoprotein production in LDLR knockout mice. Redox Biol. 2020 10; 37:101609.

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Steinkamp HM, Hathaway-Schrader JD, Chavez MB, Aartun JD, Zhang L, Jensen T, Shojaee Bakhtiari A, Helke KL, Stumpo DJ, Alekseyenko AV, Novince CM, Blackshear PJ, Kirkwood KL. Tristetraprolin Is Required for Alveolar Bone Homeostasis. J Dent Res. 2018 07; 97(8):946-953.

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Kunchithapautham K, Rohrer B. Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers. J Biol Chem. 2011 Jul 08; 286(27):23717-24.

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Young LE, Sanduja S, Bemis-Standoli K, Pena EA, Price RL, Dixon DA. The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis. Gastroenterology. 2009 May; 136(5):1669-79.

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Carballo E, Gilkeson GS, Blackshear PJ. Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction. J Clin Invest. 1997 Sep 01; 100(5):986-95.

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Taylor GA, Carballo E, Lee DM, Lai WS, Thompson MJ, Patel DD, Schenkman DI, Gilkeson GS, Broxmeyer HE, Haynes BF, Blackshear PJ. A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity. 1996 May; 4(5):445-54.

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