Proto-Oncogene Proteins c-rel
"Proto-Oncogene Proteins c-rel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.
Descriptor ID |
D020569
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MeSH Number(s) |
D12.776.260.682 D12.776.624.664.700.192 D12.776.660.767 D12.776.930.730
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Concept/Terms |
Proto-Oncogene Proteins c-rel- Proto-Oncogene Proteins c-rel
- Proto Oncogene Proteins c rel
- c-rel, Proto-Oncogene Proteins
- p68 c-rel
- c-rel, p68
- p68 c rel
- Proto-Oncogene Protein c-rel
- Proto Oncogene Protein c rel
- c-rel, Proto-Oncogene Protein
- Proto-Oncogene Proteins rel
- Proto Oncogene Proteins rel
- c-rel Protein
- Protein, c-rel
- c rel Protein
- p68(c-rel)
- rel Proto-Oncogene Product p68
- rel Proto Oncogene Product p68
- Proto-Oncogene Products c-rel
- Proto Oncogene Products c rel
- c-rel, Proto-Oncogene Products
- c-rel Proteins
- Proteins, c-rel
- c rel Proteins
- rel Proto-Oncogene Proteins
- Proto-Oncogene Proteins, rel
- rel Proto Oncogene Proteins
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-rel".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-rel".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-rel" by people in this website by year, and whether "Proto-Oncogene Proteins c-rel" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-rel" by people in Profiles.
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Cheng S, Hsia CY, Leone G, Liou HC. Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel-/- B cells. Oncogene. 2003 Nov 20; 22(52):8472-86.
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Cogswell PC, Guttridge DC, Funkhouser WK, Baldwin AS. Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3. Oncogene. 2000 Feb 24; 19(9):1123-31.
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Carrasco D, Cheng J, Lewin A, Warr G, Yang H, Rizzo C, Rosas F, Snapper C, Bravo R. Multiple hemopoietic defects and lymphoid hyperplasia in mice lacking the transcriptional activation domain of the c-Rel protein. J Exp Med. 1998 Apr 06; 187(7):973-84.