A family of protein serine/threonine kinases which act as intracellular signalling intermediates. Ribosomal protein S6 kinases are activated through phosphorylation in response to a variety of HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Phosphorylation of RIBOSOMAL PROTEIN S6 by enzymes in this class results in increased expression of 5' top MRNAs. Although specific for RIBOSOMAL PROTEIN S6 members of this class of kinases can act on a number of substrates within the cell. The immunosuppressant SIROLIMUS inhibits the activation of ribosomal protein S6 kinases.

Descriptor ID	D019893
MeSH Number(s)	D08.811.913.696.620.682.700.862 D12.644.360.600 D12.776.476.600
Concept/Terms	Ribosomal Protein S6 Kinases Ribosomal Protein S6 Kinases S6-H4 Kinase S6 H4 Kinase Ribosomal Protein S6 Kinase S6 Kinase

Below are MeSH descriptors whose meaning is more general than "Ribosomal Protein S6 Kinases".

Below are MeSH descriptors whose meaning is related to "Ribosomal Protein S6 Kinases".

Below are MeSH descriptors whose meaning is more specific than "Ribosomal Protein S6 Kinases".